ID G3PW34_GASAC Unreviewed; 556 AA.
AC G3PW34;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Semaphorin 4D {ECO:0000313|Ensembl:ENSGACP00000021823.1};
GN Name=SEMA4D {ECO:0000313|Ensembl:ENSGACP00000021823.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000021823.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000021823.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000021823.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR AlphaFoldDB; G3PW34; -.
DR STRING; 69293.ENSGACP00000021823; -.
DR Ensembl; ENSGACT00000021864.1; ENSGACP00000021823.1; ENSGACG00000016523.1.
DR eggNOG; KOG3611; Eukaryota.
DR GeneTree; ENSGT00940000159594; -.
DR InParanoid; G3PW34; -.
DR OMA; THILASY; -.
DR TreeFam; TF352903; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000016523; Expressed in muscle tissue and 12 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0007411; P:axon guidance; IEA:UniProt.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF18; SEMAPHORIN-4D; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 525..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..354
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT DOMAIN 409..481
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 556 AA; 61836 MW; 12E053EC59759A26 CRC64;
EDGRGKCSFD PSLSFTSVMV DGELYSGTSY NFLGSEPIIS RYSPSQSLLR TEYSTSWLNE
PSFVFADVIG DGGNRVDGED DKIYYFFTEV SVEYEFFGKL LIPRVARVCK GDLGGQRTLQ
KKWTSFLKAK LVCSMPELNF VFNVVHDVFI LKGAERRDTV IYGVFTSQWG NVGLSAVCAY
NMAAVEEVFS KGKYMQKATV EQSHTKWVRY NGITPSPRPG ACINNLMRDQ NISSSLHLPD
KTLQFVKDHP LLEDPVLPIG NGPRLITKDV NYTQIVRGSE RSTGTFMMSS SLEQVTHFNL
RSVINKSMVY EGEVHIMEEI QLLKNSESIK TLLLSTETRS LYAGSDSGVV QSPTAFCGRY
ASCDDCVLAR DPYCAWDPQN AACVNIFEAP SQTLRKSIQS LNGDADKCPS ASSLSLKDYR
RVTVKPGSSA ELPCLGHSNL AQVMWKSNGS ALTEASRFHL IAENGLLIYS VAPEDQGRYE
CWSVEWAPAA GKNFSRLLAA YVLALDLPPA TPGRAAYLQH NNSTALLFLF LLFFLLFLAL
AYNCYMQYPA PCLRLR
//
