ID G3PWC0_GASAC Unreviewed; 642 AA.
AC G3PWC0;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=G protein signaling modulator 1b {ECO:0000313|Ensembl:ENSGACP00000021909.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000021909.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000021909.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000021909.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GPSM family.
CC {ECO:0000256|ARBA:ARBA00006600}.
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DR AlphaFoldDB; G3PWC0; -.
DR STRING; 69293.ENSGACP00000021909; -.
DR Ensembl; ENSGACT00000021950.1; ENSGACP00000021909.1; ENSGACG00000016596.1.
DR eggNOG; KOG1130; Eukaryota.
DR GeneTree; ENSGT00940000154667; -.
DR InParanoid; G3PWC0; -.
DR OMA; HANIANC; -.
DR TreeFam; TF328344; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000016596; Expressed in telencephalon and 10 other cell types or tissues.
DR GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR003109; GoLoco_motif.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45954:SF2; G-PROTEIN-SIGNALING MODULATOR 1; 1.
DR PANTHER; PTHR45954; LD33695P; 1.
DR Pfam; PF02188; GoLoco; 4.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 3.
DR SMART; SM00390; GoLoco; 4.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50877; GOLOCO; 4.
DR PROSITE; PS50005; TPR; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 43..76
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 223..256
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 393..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 581..601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 614..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..412
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 642 AA; 71922 MW; DF8AF6DF8F001B23 CRC64;
MEASCLELAL EGERLCKAGD FKGGTAFFEA AVQVGTEDLK TLSAIYSQLG NAYFYLKEYG
KALEYHKHDL TLARTIGDRI GEGKASGNLG NTLKVLGRFD EAVVCCQRHL DISQEQRDKV
GEARALYNIG NVFHAKGKQQ LWGCTQEPGD LPPDVRDTLQ RATGFYEMNL CLVKEVGDRA
AQGRAYGNLG NTHYLLGNFV EAIKFHRQRL SIAKEFGDKA AERRAYSNLG NALIFLSQFS
TATEYYRKTL QLSRQLRDQV MEAQACYSLG NTYTLLQQYE RAIDYHLKHL YIAQELTDRV
GEGRACWSLG NAYVSLQNHK QALHYARKHL DISKEIGDRN GELTARMNVE QLMEALGVNE
SDLSPSSSEF EMQGARPKFT KRNSMDSVEL WKYSSDKNEE NQDLERIPRR SKSHVSQPGK
RKGYPDSQSS DDRPWLDSPL DADDITVQVP PPVAKLGRDP SDEDCFFDLL SKFQSSRMDD
QRCHLDEPQN GESGGGAANA VLSLNEITDP AITTSPQTEE LFDLIASSQS RRLDDQRVNV
GNLPGLRITH NNLGHLVGEG DHQEPSDDFF NMLIKCQSSR IDDQRCSPPE AGPHAPTVPD
EDFFSLIQRV QAKRMDEQRV QLPSDEQDDP QSPDAEPPAG FP
//
