ID   G3PX36_GASAC            Unreviewed;       524 AA.
AC   G3PX36;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=Zgc:136472 {ECO:0000313|Ensembl:ENSGACP00000022175.1};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000022175.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000022175.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000022175.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the protein disulfide isomerase family.
CC       {ECO:0000256|ARBA:ARBA00006347}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; G3PX36; -.
DR   STRING; 69293.ENSGACP00000022175; -.
DR   Ensembl; ENSGACT00000022217.1; ENSGACP00000022175.1; ENSGACG00000016797.1.
DR   eggNOG; KOG0190; Eukaryota.
DR   GeneTree; ENSGT00940000166046; -.
DR   InParanoid; G3PX36; -.
DR   OMA; YKMTPQT; -.
DR   TreeFam; TF106381; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000016797; Expressed in intestinal epithelial cell and 1 other cell type or tissue.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR   CDD; cd02961; PDI_a_family; 1.
DR   CDD; cd02995; PDI_a_PDI_a'_C; 1.
DR   CDD; cd02982; PDI_b'_family; 1.
DR   CDD; cd02981; PDI_b_family; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 4.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR18929; PROTEIN DISULFIDE ISOMERASE; 1.
DR   PANTHER; PTHR18929:SF58; PROTEIN DISULFIDE-ISOMERASE-LIKE PROTEIN OF THE TESTIS; 1.
DR   Pfam; PF00085; Thioredoxin; 2.
DR   Pfam; PF13848; Thioredoxin_6; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 4.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT   DOMAIN          360..489
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
SQ   SEQUENCE   524 AA;  58745 MW;  4BDF234F5DB71F06 CRC64;
     SVSGPHAYSS FSSRLKLYEY LSSHPTLCKA EDKPSPEDGD VLQLKKGNFN RALRKNKQLL
     VHFYVPLSGE GHRISAAFEG AAAELQGSEV KLAVVDVAKE KDLAKELNVT GLATIRLYLA
     GDKHNPVTCP DSDKAPHTSA SILAWLKRRA GSAADLIADL SQSESSEELT VVGFFKELDH
     EYVQVFYDAA VDLPDVNFAV TQNNEVITKY GLTHDVVLLL KQSKLIQAYK MTPQTSKEML
     IVFITVYQMD PVTEYTGQTA TQILSSPVLN HALLFVNKSS AAFKEIHSAF NGAAESYRLK
     ILFVWVDVDE PRNGRMMEYF RVRSFEAPLI RLVNLTDHVT YHLPSDTLDV HTIKAFCQSY
     LEGEAKPKMQ SQPIPEGWDQ RPVKELVGMT LEKVGFNPDK TVFVLFYLPY SAASRALFPL
     WEELAEALKG REDVVVARID ASANDINMSV QGGYPSLCLF PALYAERVVV YTGKREVKDL
     LKFVDKEMKK AKKYRVTEDE DRRKYIEAAK AEEAKKANQS KDEL
//