ID G3PXD5_GASAC Unreviewed; 192 AA.
AC G3PXD5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Transcription factor COE helix-loop-helix domain-containing protein {ECO:0000259|Pfam:PF16423};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000022274.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000022274.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000022274.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004489}.
CC -!- SIMILARITY: Belongs to the COE family. {ECO:0000256|RuleBase:RU004489}.
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DR AlphaFoldDB; G3PXD5; -.
DR Ensembl; ENSGACT00000022316.1; ENSGACP00000022274.1; ENSGACG00000016862.1.
DR GeneTree; ENSGT00950000182859; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000016862; Expressed in diencephalon and 2 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.287.4280; -; 1.
DR InterPro; IPR032201; COE_HLH.
DR InterPro; IPR003523; Transcription_factor_COE.
DR PANTHER; PTHR10747; TRANSCRIPTION FACTOR COE FAMILY MEMBER; 1.
DR PANTHER; PTHR10747:SF36; TRANSCRIPTION FACTOR COE4; 1.
DR Pfam; PF16423; COE1_HLH; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|RuleBase:RU004489};
KW DNA-binding {ECO:0000256|RuleBase:RU004489};
KW Metal-binding {ECO:0000256|RuleBase:RU004489};
KW Nucleus {ECO:0000256|RuleBase:RU004489};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Transcription {ECO:0000256|RuleBase:RU004489};
KW Transcription regulation {ECO:0000256|RuleBase:RU004489};
KW Zinc {ECO:0000256|RuleBase:RU004489};
KW Zinc-finger {ECO:0000256|RuleBase:RU004489}.
FT DOMAIN 1..26
FT /note="Transcription factor COE helix-loop-helix"
FT /evidence="ECO:0000259|Pfam:PF16423"
FT REGION 86..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 192 AA; 20246 MW; 4EB613BF6E02DF02 CRC64;
RHPGDPERLP KEVLLKRAAD LVEALYGMPH NNQEIILKRA ADLTEALYSV PRSHNQLPSL
TGSAHSGMMG VNSFSSQLAV NISEASQADK KSGYSRNSNS VSPRGYVPSS TPQQSNYNTI
TSTMNGYGAG MTNLGVPGSP GFLNGSTNSA YAIKQKSAFA PVVRPQTSPP PTCTTTNGSN
LQAMAGLIVP PM
//
