ID G3PY20_GASAC Unreviewed; 1014 AA.
AC G3PY20;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=MAM domain-containing protein {ECO:0000259|PROSITE:PS50060};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000022509.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000022509.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000022509.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR AlphaFoldDB; G3PY20; -.
DR STRING; 69293.ENSGACP00000022509; -.
DR Ensembl; ENSGACT00000022551.1; ENSGACP00000022509.1; ENSGACG00000017043.1.
DR eggNOG; KOG1095; Eukaryota.
DR GeneTree; ENSGT00940000164732; -.
DR InParanoid; G3PY20; -.
DR OMA; ENGTCDW; -.
DR TreeFam; TF330345; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000017043; Expressed in intestinal epithelial cell.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR CDD; cd00112; LDLa; 2.
DR CDD; cd06263; MAM; 5.
DR Gene3D; 2.60.120.200; -; 6.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR000998; MAM_dom.
DR PANTHER; PTHR23282; APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR; 1.
DR PANTHER; PTHR23282:SF101; RT07201P-RELATED; 1.
DR Pfam; PF00057; Ldl_recept_a; 1.
DR Pfam; PF00629; MAM; 6.
DR PRINTS; PR00261; LDLRECEPTOR.
DR PRINTS; PR00020; MAMDOMAIN.
DR SMART; SM00192; LDLa; 2.
DR SMART; SM00137; MAM; 5.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 6.
DR SUPFAM; SSF57424; LDL receptor-like module; 2.
DR PROSITE; PS50068; LDLRA_2; 2.
DR PROSITE; PS00740; MAM_1; 1.
DR PROSITE; PS50060; MAM_2; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT DOMAIN 1..155
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 202..363
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 428..499
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 514..674
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 676..838
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 840..1008
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT REGION 11..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 700..721
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..551
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 162..174
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 169..187
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 412..427
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 1014 AA; 111142 MW; 9F0A44337E097D94 CRC64;
CSFENGTCGW DDRSSGQCQW TRGRNGTGNT GPSVDNTLST ELGWYLAVAP KRGDDVSLAA
VHSPPMRQAS ATCTLHFHYS MNGEDGEMLN VLLNEGSRTT ALWWLSGNHG DAWHPAEVTV
GRIPQDFTVL FEACRSFNRP GHVAIDDIHF TNCTLPEPEP SCPPNTFVCN NSVCVEHSRV
CDFSDDCGDW SDERKLESQA HLDVHFEQGL CFWEKNEVDT AAVGWTHHRG QEAWPKHGPP
RDHTYNSDAG HYAVPGNLIE NSETSETLSK TLLPSSNCTV RFFYFGLDDV TARLTARSRM
LRSGSGDALL WCWENSQSFS WRRAEVTFSS SVNSKIVFRY ERGDGLGGLV ALDDVSFSRE
CLFDPDNNKL PDPSTTSAPP TSATAPCQAL QDGEFLCWRS PDKVCIPAAL RCDYHPDCPQ
AEDEDGCGGC TFERDQCEWT DTSDGHGRWQ RQRASNDTEP PTDHTAGTGY YMRVNLSRES
TQTEARLQSP PLAPSSLYCQ ILPAPAAVSA LAAGGCSFED GLCVWVQGAE DELDWLSNSG
PTETPNTGPA GDHTTGKGKY IYIKSSRPSV KGNVAQLKST LLPSAGDQGY CFTFWYHMFG
ATAGSLRMLL LTAEPLKKTL VWQNSGNQGD EWLRVQSHVT SQNVHQVILE ATVGGEAGDI
AIDDISLVGG PCPASDACDF EEGSCGWQQG TTDDFDWVRM SGSTHNPNTG PESDHTTNTP
AGHYYCLPSS AADAAGQTAK MSSPLYPAGK GACLQLWYHM YGRGTGLLNV YQQSEEGKRA
LIFSQTGNQG RLWRFAQASL LPRVQPYRIV VEGVKAGPTQ EGDMAFDDVQ LTDTQCPPPG
HCDFESNWCS WSNLGGGVDQ GDWLRGRGAS PNPNTGPSVD HTTNSTHGFY LYVDSSVGEW
GDLSFLVSEV FQPSPRGHCL TFWYHMYGSH VGTLRVYIND RKTHAGDNEE GILKWIETGN
RGDEWQEASV TVKHSEAFWF VFVYQRGMNT GGDVSLDDIT ILPGGCYSEP PIDP
//
