ID G3Q1G3_GASAC Unreviewed; 1027 AA.
AC G3Q1G3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=ST18 C2H2C-type zinc finger transcription factor {ECO:0000313|Ensembl:ENSGACP00000023711.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000023711.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000023711.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000023711.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MYT1 family.
CC {ECO:0000256|ARBA:ARBA00010194}.
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DR STRING; 69293.ENSGACP00000023711; -.
DR Ensembl; ENSGACT00000023757.1; ENSGACP00000023711.1; ENSGACG00000017947.1.
DR eggNOG; KOG3803; Eukaryota.
DR GeneTree; ENSGT00940000159905; -.
DR InParanoid; G3Q1G3; -.
DR OMA; QVNNCAH; -.
DR TreeFam; TF317299; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000017947; Expressed in diencephalon and 3 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 4.10.320.30; -; 6.
DR InterPro; IPR013681; Myelin_TF.
DR InterPro; IPR002515; Znf_C2H2C.
DR InterPro; IPR036060; Znf_C2H2C_sf.
DR PANTHER; PTHR10816; MYELIN TRANSCRIPTION FACTOR 1-RELATED; 1.
DR PANTHER; PTHR10816:SF9; SUPPRESSION OF TUMORIGENICITY 18 PROTEIN; 1.
DR Pfam; PF08474; MYT1; 1.
DR Pfam; PF01530; zf-C2HC; 5.
DR SUPFAM; SSF103637; CCHHC domain; 6.
DR PROSITE; PS51802; ZF_CCHHC; 5.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU01143}.
FT DOMAIN 467..669
FT /note="Myelin transcription factor 1"
FT /evidence="ECO:0000259|Pfam:PF08474"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 35..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 340..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 510..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 905..961
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 156..171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..191
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..211
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..247
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1027 AA; 112648 MW; 37C29E2564062332 CRC64;
MDSEGEEQTL RTRNGDTGVP LTAVVKLRSV PYGSVARKRS AQEGVQGAPV NKRKSLLMKP
RHYSPSEACE EESEDLAPPQ DKEEPRNIDT PAVIVRFGGH FLLKKKQKLD EQTGGRRIKF
SCFSQKVTQN LKPLKALWRI TVDIQFLSRV LEGSQKNGYD AESSDSLGCS EVTSDGEPDA
GDEELPDSER DDQTEDLMSG ASSSVLTETP GRPSVSRRVC PAAAPPPPRK TRRGGSGPRE
RRSPARRGAA EVQAAAAEED GEGEAEAERP PQPDGWGLGL HERGLEMGRG RVNFSLLEQA
IALQTEQRQV LHHAYREMDR FLMEQMTSER RHHRMMDMDG RLSFHGGKDS PRTDKKDIKC
PTPGCDGTGH VTGLYPHHRS LSGCPHKVRV PPEXMHENVL KCTRPCTRRG HVNSNRSTHR
SLSGCPIAAA VKVSKPQEES PKCRQTPDCS PRAIGLMKKF EMNQLNYRLS HPVAALKTSL
AKDMDKYSRI RFDYASFDAQ VFGKQPLMGA SQDQEMPHFP DSPQRYHAFL GAPGGGLPAS
GQRSPPSQFR KEDGLQAAAA TAAILNLSTR YRKNMEAVAG RPLATSTKDV PIEVDENGTL
DLSMKKSKDS GKGPLDDSLS LAEAAKGGGV LVGPAFYQPL CERDGWDGPL PLHFNKAHVS
PDAEVQTDAR HNRRPKNFLN NGSVMSPQAK LLLRDAKKEP LNCPTPGCDG SGHVTGNYAS
HRSVSGCPLA DKTLKSLMAA NSQELKCPTP GCDGSGHVTG NYASHRSLSG CPRARKGGLK
LTPDKDDKDE QELKCPVMGC DGQGHTSGKY TSHRSAGSCP LAAKRQKESS VSGLPFAWKA
NKQELPHCPL PGCNGLGHAN NVFATHRSLS GCPLNAQSIK KKHSEEEMMT IKLKTSSGVE
NKEDIQHLDH EIQELNESNM KIEADMMQLQ TQQISSMECN LRTIEEENRM IEQHNDGLLK
ELARLSQALI NSLTDIQLPQ MGPISEQNFE AYVNTLTDMY NNSEHEYSPE CKALLDNIKQ
AIKGIHV
//
