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Database: UniProt
Entry: G3Q1R7_GASAC
LinkDB: G3Q1R7_GASAC
Original site: G3Q1R7_GASAC 
ID   G3Q1R7_GASAC            Unreviewed;       886 AA.
AC   G3Q1R7;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   20-JUN-2018, entry version 37.
DE   SubName: Full=N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a {ECO:0000313|Ensembl:ENSGACP00000023815};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000023815, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000023815}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000023815}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
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DR   STRING; 69293.ENSGACP00000023815; -.
DR   Ensembl; ENSGACT00000023862; ENSGACP00000023815; ENSGACG00000018023.
DR   eggNOG; KOG3703; Eukaryota.
DR   eggNOG; ENOG410XQN4; LUCA.
DR   GeneTree; ENSGT00760000119023; -.
DR   InParanoid; G3Q1R7; -.
DR   OMA; RYILEIH; -.
DR   TreeFam; TF313193; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015016; F:[heparan sulfate]-glucosamine N-sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:1904888; P:cranial skeletal system development; IEA:Ensembl.
DR   InterPro; IPR021930; Heparan_SO4_deacetylase.
DR   InterPro; IPR037359; NST/OST.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000863; Sulfotransferase_dom.
DR   PANTHER; PTHR10605; PTHR10605; 1.
DR   Pfam; PF12062; HSNSD; 1.
DR   Pfam; PF00685; Sulfotransfer_1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007635};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     21     40       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       27    519       HSNSD. {ECO:0000259|Pfam:PF12062}.
FT   DOMAIN      609    858       Sulfotransfer_1. {ECO:0000259|Pfam:
FT                                PF00685}.
SQ   SEQUENCE   886 AA;  101038 MW;  C989F71FEC5A65FD CRC64;
     MLGCVTRLRR LVRLLPLQTS LLLLFLFCTV SVFISAYFLY GVKRELEPSG GGVSGAEGAS
     ADSDDPRVTP SRLLPLRGVP GAPESPAEPV CLKIIYCIYK FFNTKMLTLV HHNSFTAYLR
     SKFILGNGPC GPLNSNKKNT LKHCLISLEL VNTPHFFLEL LKTGCHICAK LSLLGFLLLA
     NENSLLSAQL KGFPLFLHSN LGLKDCTVNP KSPLLFITRS GQPLPGPLPG DDWTVFQSNH
     STYEPVLLAK TQSAESIASM GQNAALLPSV VQDLGLHDGI QRVLFGNNLV FWLHKLVFVD
     AVAFLTGKRL SLSLERYVLV DVDDIFVGKE GTRMKVPDVK ALLETQRELR THVPNFTFNL
     GFSGKFFHAG SDEEDLGDDL LLSFVKEFWW FPHMWSHMQP HLFHNQSVLA EQMLLNKKFA
     IEHGIPTNMG YAVAPHHSGV YPVHIQLYDA WKKVWGIKVT STEEYPHLKP ARFRRGFIHS
     GISVLPRQTC GLFTHTIFYK DYPGSPNELD KLINGGELFQ TVLLNPISIF MTHLSNYGND
     RLGLYTFKSL VMFLQTWTNL KMQTLPPVQL AQKYFSLFPS ERDPLWQDPC EDKRHKDIWS
     KEKTCDRFPK LLVIGPQKTG TTALYLFLGM HPDLTSNYPS KETFEEIQFF NGHNYHRGID
     WYMEYFPLPS NTSSDYYFEK SANYFDSEVA AQRAAALLPK AKIITILINP ADRAYSWYQH
     QRAHDDPVAL KYSFHDVITA GHNAPVRLRV LQNRCLVPGW YAIHLDRWLN FYHSSQLLVL
     DGQMLKTEPA SIMDKIQKYL SLVNVINYHK ILAFDPKKGF WCQLLEGGKT KCLGKSKGRR
     YPDMDPESQT FLREYYRDHN IELSKLLYKM GQPLPSWLRE ELVHTR
//
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