ID G3Q2K9_GASAC Unreviewed; 1833 AA.
AC G3Q2K9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Programmed cell death 11 {ECO:0000313|Ensembl:ENSGACP00000024108.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000024108.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000024108.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000024108.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
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DR STRING; 69293.ENSGACP00000024108; -.
DR Ensembl; ENSGACT00000024155.1; ENSGACP00000024108.1; ENSGACG00000018233.1.
DR eggNOG; KOG1070; Eukaryota.
DR GeneTree; ENSGT00390000012228; -.
DR InParanoid; G3Q2K9; -.
DR OMA; GQYLRAY; -.
DR TreeFam; TF105697; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000018233; Expressed in embryo and 12 other cell types or tissues.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR CDD; cd05702; S1_Rrp5_repeat_hs11_sc8; 1.
DR CDD; cd05693; S1_Rrp5_repeat_hs1_sc1; 1.
DR CDD; cd05694; S1_Rrp5_repeat_hs2_sc2; 1.
DR CDD; cd05695; S1_Rrp5_repeat_hs3; 1.
DR CDD; cd05697; S1_Rrp5_repeat_hs5; 1.
DR CDD; cd05698; S1_Rrp5_repeat_hs6_sc5; 1.
DR CDD; cd04461; S1_Rrp5_repeat_hs8_sc7; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 9.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR045209; Rrp5.
DR InterPro; IPR048058; Rrp5_S1_rpt_hs11_sc8.
DR InterPro; IPR048059; Rrp5_S1_rpt_hs1_sc1.
DR InterPro; IPR003029; S1_domain.
DR InterPro; IPR008847; Suf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR23270; PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5; 1.
DR PANTHER; PTHR23270:SF10; PROTEIN RRP5 HOMOLOG; 1.
DR Pfam; PF00575; S1; 4.
DR Pfam; PF05843; Suf; 1.
DR SMART; SM00386; HAT; 5.
DR SMART; SM00316; S1; 12.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 9.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50126; S1; 10.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT DOMAIN 88..175
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 191..256
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 279..342
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 451..520
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 540..609
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 628..699
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 721..790
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1008..1083
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1201..1269
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1295..1367
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1385..1409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1464..1486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1508..1545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..32
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..63
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1464..1479
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1520..1545
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1833 AA; 203160 MW; BAD81E0A67808CC7 CRC64;
MASMEEDFPR GGPAKKLTES KTKVERTEVD NLFQVESNEQ AETKKRKGAG KDADQKFKKP
KTGTGDHLTL NAEAKCVEIL HIKNLQEGTL LLGCVKEVTD FEVTVGLPCG MEGFLSIMNI
CDSYTKLLNE QLDSDDTEEI CSLQHLFYPG MVLRCVLAKL DVRKEGSLSI QLSINPKLVN
KALSSSSLKA GMALSGCVES VEDHGCIVDI GVSGTKAFLP KKAQENIPEE LKVGQYLTFQ
VEGVKNDGRV VHLSVRPPTA VRACAESQQG WNLTNLLPGL LVQATIKKVT KHGLILQFLS
SFTGQVDVLH MEPEQSYTEG NEVRACVLYV EPSTRLLGLS LRSYLVQPGA RLEHAPAGGE
RIGEVVKDCK VVATHHMSGA MVVLPDKTLT FAHRNHLKEP NEPPTDNRVL AKTTHTCRIL
SFSPMDQIYF VSVRKSVVER RFHRYHDIQA GQLVEGTVSV LIEHGMVVHL SSHIKGLVPR
THLSDILLKN PERKYVPGMK IKCRVLSVDA EKKNLYLSRK KALVESSLPL FLSYADARPG
LVSHGYVVSV KDFGCIVRFY NDVRGLVPLN ELSSQPIINP EEMFYVGQVL KAKVLQCNPD
KAKLVLSFKA AEGDAEEVAN PQFDCEVGQR LEARIQKKSV TGLEVAILPD DIRAVIPTMH
LSDHLSNCPL LLESMQEGDT ISNLICFSKN KRNIAISKKP TVRWSLEQGV FAKNFSEVTV
GMQLIGWIKN LMPYGVFVEF PYGLVGLAPK SAMTDKFISN TAIAFQPGQT VMAKVTNLDE
EKQRFLVTLK ISEVMCPEGD AQTRLINGLQ ERRAVAETLA VREDSDLRQQ LAALIVGQKL
KLTVDTVDSG ARFKSDNLAG ATIKATEDQV IGVELTSGQK VTAVVLHVDI LSSCVHVSIL
PKLVAKKKSL AEGSKHTATV QHIDQDFATV SLGDTAQLTV IQTSSHLNEV FPSESDKLKA
GMSLSVEVIE PRCQELQGLA LVSWVFGSPK EHVSTFKHWA SSRGHRFGDI VRGKVRAVKP
ASIQVTLEDG RTGSVHVSEV VELAEVRPGS FPTSTVQVGS EITARVIGGR EVSTHRFLPF
SHPKFKYNIP ELTLIPSKLD ENKDFKPVTP EEKINGYTVG EEVTCFVSKF NQKRKTLEVT
TDPCVTMTVD LLGMITDPKY SSHPEKLYKI GQAVLAKVVE VNSDPISCTL SLTGVHQLEK
GSVTLGVVTN IHPQFGVQVK LPFGNMGTVA VTDLSDAYRP TPFDAYSKDK LLRCFLLGNE
NGKWQLSLRP SRLYPQQSKP VKDLEVLSVD HLKEGKTIRG YVKSVGQHGV FIRLSTSITG
RAQLQQCTKY LVKDDTVLSK HLPLNTLLTT KICSIDQEEG LVHLSLLPED TGKPDVLPET
LGLQLRPAGE EKKKNKKTTS VSKAATTKKK RAASESVQLL SKTVIKWKQP SSMVTDARVS
LQLESPITKK AKTDDNDSGV EVYFREEEDK SDKEPKSNSV KKVTPSAAVP SRLQVAAGFS
WDAHLSSLKP ASAAQEGDSS DGEDQDHSNK PQKRSRHELQ QEKKAAEKAL VQRETELMDP
SLRPQDAAAF ERLILGSPNS SLLWLQYMAH HLQATQIEQA RAVAERALKT ISFREEQEKL
NVWVALLNLE NMYGSEESLK VVFERAQQFC EPMPVYQQLA DIYAKSNKTK EAEGLYKTMV
KRFRQNKAVW LSYGTFLLQQ GQSDGATVLL QRALKSLPTK ESVDVIAKFA QLEFRYGDPE
KGRTMFDKVL TSYPKRTDLW SVFLDLMFKH GSQKEVRALF DRVIALSVSV KKIKFFFKRY
LEYEKKHGTP QTIQAVKEKA VEFVEARGNE AAN
//
