ID   G3Q5P7_GASAC            Unreviewed;       619 AA.
AC   G3Q5P7;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=VWFD domain-containing protein {ECO:0000259|PROSITE:PS51233};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000025203.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000025203.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000025203.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; G3Q5P7; -.
DR   Ensembl; ENSGACT00000025252.1; ENSGACP00000025203.1; ENSGACG00000019056.1.
DR   GeneTree; ENSGT00940000165245; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000019056; Expressed in mesonephros and 3 other cell types or tissues.
DR   CDD; cd19941; TIL; 1.
DR   Gene3D; 2.10.25.10; Laminin; 1.
DR   InterPro; IPR036084; Ser_inhib-like_sf.
DR   InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR   InterPro; IPR001846; VWF_type-D.
DR   PANTHER; PTHR11339; EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED; 1.
DR   PANTHER; PTHR11339:SF289; MUCIN-19-LIKE; 1.
DR   Pfam; PF08742; C8; 2.
DR   Pfam; PF00094; VWD; 2.
DR   SMART; SM00832; C8; 1.
DR   SMART; SM00216; VWD; 1.
DR   SUPFAM; SSF57567; Serine protease inhibitors; 1.
DR   PROSITE; PS51233; VWFD; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..619
FT                   /note="VWFD domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003450506"
FT   DOMAIN          368..539
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
SQ   SEQUENCE   619 AA;  71077 MW;  610FE5B93D3639AC CRC64;
     MTTQRWILAF CFSLASDTCR TFGSGIVQPF KGESYYVRSD CQFILISFTV NGKEYSVTIR
     RGHNGLLVQV EIIINKVTTL LQNGHVVVKN KKFELREKTG LGDRHQWRRQ RLKVTHPCNR
     KYQHIFKYGI YSRLRSSLLP FTVTWHNVHG GINSLWVTLE SELNTTTSGL CGKQNIAGHR
     DKLIRDSKLH DHKCKTSSPV LQKNDICRQF FQEIKDCVQY NISHYQRLCE ENIFGFENNQ
     SVFCPFFKEF ASQCNQTRIN RFWRRLTKCA EPRCPGDLIY REKGPAVIPS CSNPKPLPFY
     QELTESCACP EGKVLNNGAK GYRCIPWSNC SCEFAGKSYR NGEIRRSKCH SCTCHGVVWR
     CSENFCHRRC VIEVPFVTTF DGKKYVLPYK CAYLASKGPS WRIRIHFSRK GLYLRKVVVR
     LPGELIVFRK NKVLWNWQEI TQFHQFQETL AKIYWCLTSQ VHTTPVIFQI QLSPEIQLFI
     DAPNQSKSDD KIEGLCGNSN RNTTDDFTTE TGFFPNSVQL FALSWIMGNC QGNIPTTCTK
     RENENYAHEK CAVLNQPTGV FAQGHPHIPT AYYYKACIQR ICNSGRSQKE ALCIGLASYA
     KACAGVGVVI GDWKKNMGC
//