ID G3Q8K1_GASAC Unreviewed; 392 AA.
AC G3Q8K1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Cyclic AMP-dependent transcription factor ATF-4 {ECO:0000256|ARBA:ARBA00018846};
DE AltName: Full=Activating transcription factor 4 {ECO:0000256|ARBA:ARBA00032136};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000026215.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000026215.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000026215.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the bZIP family.
CC {ECO:0000256|ARBA:ARBA00007163}.
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DR AlphaFoldDB; G3Q8K1; -.
DR STRING; 69293.ENSGACP00000026215; -.
DR Ensembl; ENSGACT00000026266.1; ENSGACP00000026215.1; ENSGACG00000019842.1.
DR eggNOG; KOG4571; Eukaryota.
DR GeneTree; ENSGT00530000063801; -.
DR InParanoid; G3Q8K1; -.
DR OMA; WMTEKID; -.
DR TreeFam; TF316136; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000019842; Expressed in pharyngeal gill and 13 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:UniProt.
DR CDD; cd14692; bZIP_ATF4; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR PANTHER; PTHR13044; ACTIVATING TRANSCRIPTION FACTOR ATF 4/5; 1.
DR PANTHER; PTHR13044:SF2; CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-4; 1.
DR Pfam; PF00170; bZIP_1; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 318..381
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 23..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 336..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 283..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..336
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 392 AA; 41163 MW; 791CC91F4A55D471 CRC64;
MTLCPLAAEA LYLGPSLLTA DPMGPLLDQN EEALSPSSSL EGKAPASPPL SFSSPPVSPT
PPSLFLGTKA RADSPSLPWL GAGDLLSATI GPDDGNDDAF AGMDWMSEKI DLSGFDLDSL
MGSSDECPSS PEDLLASLDS HVDLDVDSFN ASVSSPHGGL ELCMPLPSLE GAEVAPDQQV
AKAEPPSPAS TLELGSEVDV PDAEKTPARL SAAIIPGPSE VLLTSSPIVL SLPTSGHLVV
VLANQDEPPL VSIPDPSAIP PPPSDCDSDS GIESVAGSPA RLQPPTAGSS RTKPYSKPEP
SSTTKTPKVK SVSGAPKVEK KLKKMEQNKT AATRYRQKKR VEQDLLNTEC EELEKRNGEL
SDKADSISRE IQYLKDLMEE VRKRRVKSSS VA
//
