ID G3QAU8_GASAC Unreviewed; 728 AA.
AC G3QAU8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Cytoplasmic polyadenylation element binding protein 4 {ECO:0000313|Ensembl:ENSGACP00000027014.1};
GN Name=CPEB4 {ECO:0000313|Ensembl:ENSGACP00000027014.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000027014.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000027014.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000027014.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RRM CPEB family.
CC {ECO:0000256|ARBA:ARBA00010347}.
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DR AlphaFoldDB; G3QAU8; -.
DR STRING; 69293.ENSGACP00000027014; -.
DR Ensembl; ENSGACT00000027066.1; ENSGACP00000027014.1; ENSGACG00000020430.1.
DR eggNOG; KOG0129; Eukaryota.
DR GeneTree; ENSGT00940000154998; -.
DR InParanoid; G3QAU8; -.
DR OMA; XRTYGRR; -.
DR TreeFam; TF317658; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000020430; Expressed in intestinal epithelial cell and 13 other cell types or tissues.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:InterPro.
DR GO; GO:0045182; F:translation regulator activity; IEA:InterPro.
DR CDD; cd19757; Bbox1; 1.
DR CDD; cd12724; RRM1_CPEB2_like; 1.
DR CDD; cd12726; RRM2_CPEB2_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 4.10.640.40; Cytoplasmic polyadenylation element-binding protein, ZZ domain; 1.
DR InterPro; IPR032296; CEBP_ZZ.
DR InterPro; IPR038446; CEBP_ZZ_sf.
DR InterPro; IPR034819; CPEB.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR12566; CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB; 1.
DR PANTHER; PTHR12566:SF2; CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 4; 1.
DR Pfam; PF16366; CEBP_ZZ; 1.
DR Pfam; PF16367; RRM_7; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 471..558
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 579..657
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 47..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 73..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..373
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 728 AA; 79433 MW; 06A0876F64F21346 CRC64;
MGDYGFGVLV QNNTGNKSAF PVRIHPHLQP PHHHQNVSQS PAAFINSTTA AGNGTTGGSP
WLFPASATHN SVQDEILGGP EKPKAQQQQE MQETQEKQQQ LSPGSHQEGG GGGGIISELE
KARSDEAKTD NGTSEGSNGK EKQLRLESPV LTGFDYHETS GLGGTGPVQS STTSSSLTGF
NNWSAAIPPA PSTIINEDVS FFNPASANNG ALLFPNFSHH VSPGFGGNFS PQIGPAAALS
QHHAAPPPHP HFQHPHNQHQ QHRRSPASPH PPPPFPHRNA AFNQLPHLSN SLNKPPSPWG
PASYHSTSPS PGSSTSWSPG GGYGSGSGSW GGSQGRDYRR GLNGGMTPIN SISPLKKTFP
NNHVASQKYP RNSPAAFNPK SWMDDGVGRS DNIFPFQERT RSFDSFNMNT LESSLIDILR
AEQDTLKGHS SLFPMEDGFP DDDRGEQGLA GLGSPHCFPH QNGERVERYS RKVFVGGLPP
DIDEDEITAS FRRFGHLFVD WPHKAESKSY FPPKGYAFLL FQDESSVQAL IDACIEEDGK
LYLCVSSPTI KDKPVQIRPW NLNDSDFVMD GSQPLDPRKT IFVGGVPRPL RAVELAMIMD
RLYGGVCYAG IDTDPELKYP KGAGRVAFSN QQSYIAAISA RFVQLQHGEI DKRVEVKPYV
LDDQLCDECQ GTRCGGKFAP FFCANVTCLQ YYCEYCWAAI HSRAGREFHK PLVKEGGDRP
RHISFRWN
//
