ID   G3QBZ4_GASAC            Unreviewed;       843 AA.
AC   G3QBZ4;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   SubName: Full=Heat shock protein 4a {ECO:0000313|Ensembl:ENSGACP00000027410.1};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000027410.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000027410.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000027410.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000256|ARBA:ARBA00007381}.
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DR   AlphaFoldDB; G3QBZ4; -.
DR   STRING; 69293.ENSGACP00000027410; -.
DR   Ensembl; ENSGACT00000027462.1; ENSGACP00000027410.1; ENSGACG00000020732.1.
DR   eggNOG; KOG0103; Eukaryota.
DR   GeneTree; ENSGT00940000156067; -.
DR   InParanoid; G3QBZ4; -.
DR   OMA; IQIQLRY; -.
DR   TreeFam; TF105043; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000020732; Expressed in telencephalon and 12 other cell types or tissues.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 2.
DR   Gene3D; 3.30.30.30; -; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR45639:SF6; HEAT SHOCK 70 KDA PROTEIN 4; 1.
DR   PANTHER; PTHR45639; HSC70CB, ISOFORM G-RELATED; 1.
DR   Pfam; PF00012; HSP70; 2.
DR   PRINTS; PR00301; HEATSHOCK70.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 2.
DR   SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Methylation {ECO:0000256|ARBA:ARBA00022481};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT   REGION          507..574
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          780..843
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        797..823
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   843 AA;  94095 MW;  823F4CB6CA699359 CRC64;
     MSVVGFDLGF QSCYVAVARA GGIETVANEY SDRCTPSVIS FGPRNRSIGA AAKSQVVTNC
     RNTVQAFKRF HSRAFSDPYV QSAKSNLVYD LAEMPSGATG IKVMYMEEER VFSIEQVTGM
     LLSKLKETAE SALKKPVADC VISVPSYFTD SDRRSVMDAA QIAGLNCLRL MNETTAVSLA
     YGIYKQDLPA PEEKPRNVVF VDVGHSGYQV SVCAFNKGKL KILATAFDAE LGGKALDEIL
     VNHFCEEFGK KYKLDVKSKP RALVRLHQEC EKLKKLMSAN SSDLPLNIEC FMNDIDVSGK
     LNRGQFEEMC AGHLAKVEGP LRSVMEQAKL KKEDIYAVEI VGGASRIPSI KERISRFFGK
     ELSTTLNADE AVARGCALQC AILSPAFKVR EFSITDVVPY SISLKWNSAA EEGLSDCEVF
     QKNHAAPFSK VLTFFRKEPF TLEGYYSNPK ELPYPNSHIG PFLIHNLVPH ASGESSKVKV
     KVRVNVHGMF SVSSASLIEV LKTAEGEEQL ETDHPAKEEE NKMHVDQDDP KLQTGDNGEN
     KSEVEEMETT EDSKQAKKND QPPQAKKPKV KTKTVELPVE HKLLGQLSDD VLNMSVENEG
     QMIMQDKLEK ERNDAKNNVE EYVYDMRDKL HGVLEKFVNE AHRDAFSLKL EDTETWLYED
     GEDQQKQVYI DKLAELKEMG QPIFERYMEA EERPRAFQEL GRLIQMYMKI IDAYKAKDEL
     YDHMDELEVT SVEKQVKAAM IWMNGKMNQQ NNQDLTLEPV VKVAEIQAKI KELYSACNPV
     VSKPKPKAEL PQEEKTENGP VNGQEGQEGT EGTDSQPGNS DKATPAGAEQ GAAEKKLPDM
     DID
//