ID G3QF48_GORGO Unreviewed; 113 AA.
AC G3QF48;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 {ECO:0000256|ARBA:ARBA00016383};
DE AltName: Full=Complex I-B14.5a {ECO:0000256|ARBA:ARBA00033401};
DE AltName: Full=NADH-ubiquinone oxidoreductase subunit B14.5a {ECO:0000256|ARBA:ARBA00030360};
GN Name=NDUFA7 {ECO:0000313|Ensembl:ENSGGOP00000000912.3};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000000912.3, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000000912.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000000912.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000000912.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000256|ARBA:ARBA00003195}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC {ECO:0000256|ARBA:ARBA00011533}.
CC -!- SIMILARITY: Belongs to the complex I NDUFA7 subunit family.
CC {ECO:0000256|ARBA:ARBA00005482}.
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DR EMBL; CABD030111340; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004059969.1; XM_004059921.2.
DR AlphaFoldDB; G3QF48; -.
DR Ensembl; ENSGGOT00000000931.3; ENSGGOP00000000912.3; ENSGGOG00000000924.3.
DR GeneID; 101132047; -.
DR KEGG; ggo:101132047; -.
DR CTD; 4701; -.
DR GeneTree; ENSGT00390000006553; -.
DR HOGENOM; CLU_149566_0_0_1; -.
DR OrthoDB; 5387924at2759; -.
DR TreeFam; TF319126; -.
DR Proteomes; UP000001519; Chromosome 19.
DR Bgee; ENSGGOG00000000924; Expressed in heart and 5 other cell types or tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR InterPro; IPR009947; NDUA7.
DR PANTHER; PTHR12485:SF1; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 7; 1.
DR PANTHER; PTHR12485; NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B; 1.
DR Pfam; PF07347; CI-B14_5a; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT REGION 29..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 85..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 113 AA; 12622 MW; 0E945CA429AD3EF8 CRC64;
MASATRLIQR LRNWASGHDL QAKLQLRYQE ISKRTQPPPK LPVGPSHKLS NNYYCTRDGR
RESVPPSIIM SSQKALVSNK PAESSAVAAT EKKAVTPAPP IKRWELSSDQ PYL
//
