ID G3QFP5_GORGO Unreviewed; 336 AA.
AC G3QFP5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Ring finger protein 130 {ECO:0000313|Ensembl:ENSGGOP00000001122.3};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000001122.3, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000001122.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000001122.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000001122.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030042784; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030042785; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030042786; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030042787; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030042788; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030042789; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030042790; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030042791; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030042792; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030042793; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G3QFP5; -.
DR STRING; 9593.ENSGGOP00000001122; -.
DR Ensembl; ENSGGOT00000001146.3; ENSGGOP00000001122.3; ENSGGOG00000001137.3.
DR GeneTree; ENSGT00940000157465; -.
DR HOGENOM; CLU_049885_2_1_1; -.
DR InParanoid; G3QFP5; -.
DR OMA; FCLVADH; -.
DR Proteomes; UP000001519; Chromosome 5.
DR Bgee; ENSGGOG00000001137; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR CDD; cd02122; PA_GRAIL_like; 1.
DR CDD; cd16803; RING-H2_RNF130; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46539; E3 UBIQUITIN-PROTEIN LIGASE ATL42; 1.
DR PANTHER; PTHR46539:SF27; RING FINGER PROTEIN 130; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 111..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 181..222
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 336 AA; 37703 MW; 8BA078263F419BA5 CRC64;
ADHLGCDPQT RFFVPPNIKQ WIALLQRGNC TFKEKISRAA FHNAVAVVIY NNKSKEEPVT
MTHPGTGDII AVMITELRGK DILSYLEKNI SVQMTIAVGT RMPPKNFSRG SLVFVSISFI
VLMIISSAWL IFYFIQKIRY TNARDRNQRR LGDAAKKAIS KLTTRTVKKG DKETDPDFDH
CAVCIESYKQ NDVVRILPCK HVFHKSCVDP WLSEHCTCPM CKLNILKALG IVPNLPCTDN
VAFDMERLTR TQAVNRRSAL GDLAGDNSLG LEPLRTSGIS PLPQDGELTP RTGEINIAVT
SGHFFHRNSL SPRSLVYESE FSTIEPSLDM YDENKT
//
