ID G3QH66_GORGO Unreviewed; 196 AA.
AC G3QH66;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Sterile alpha motif domain containing 12 {ECO:0000313|Ensembl:ENSGGOP00000001688.3};
GN Name=SAMD12 {ECO:0000313|Ensembl:ENSGGOP00000001688.3};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000001688.3, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000001688.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000001688.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000001688.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030060687; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030060688; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030060689; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030060690; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030060691; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030060692; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030060693; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030060694; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030060695; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030060696; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G3QH66; -.
DR STRING; 9593.ENSGGOP00000001688; -.
DR Ensembl; ENSGGOT00000001726.3; ENSGGOP00000001688.3; ENSGGOG00000001716.3.
DR eggNOG; ENOG502RXXU; Eukaryota.
DR GeneTree; ENSGT00390000008161; -.
DR InParanoid; G3QH66; -.
DR OMA; LCRISFI; -.
DR TreeFam; TF325918; -.
DR Proteomes; UP000001519; Chromosome 8.
DR Bgee; ENSGGOG00000001716; Expressed in prefrontal cortex and 5 other cell types or tissues.
DR GO; GO:0009898; C:cytoplasmic side of plasma membrane; IBA:GO_Central.
DR GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IBA:GO_Central.
DR CDD; cd09510; SAM_aveugle-like; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR039144; Aveugle-like_SAM_dom.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR20843; STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10; 1.
DR PANTHER; PTHR20843:SF2; STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 12; 1.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT DOMAIN 72..138
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
SQ SEQUENCE 196 AA; 22418 MW; C555729AE857F567 CRC64;
LHCGLNPRGI DHPAHAEGIK LQIEGEGVES QSIKNKNFQK VPDQKGTPKR LQAEAETAKS
ATVKLSKPVA LWTQQDVCKW LKKHCPNQYQ IYSESFKQHD ITGRALLRLT DKKLERMGIA
QENLRQHILQ QVLQLKVREE VRNLQLLTQG TLLLPDGWMD GEIRRKNTLL LGQTGVRENL
LLFLHRISII ENSIQI
//
