ID G3QMM4_GORGO Unreviewed; 213 AA.
AC G3QMM4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=Motile sperm domain-containing protein 1 {ECO:0000256|ARBA:ARBA00020941};
GN Name=MOSPD1 {ECO:0000313|Ensembl:ENSGGOP00000003766.3};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000003766.3, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000003766.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000003766.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000003766.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CABD030128490; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004064943.1; XM_004064895.2.
DR AlphaFoldDB; G3QMM4; -.
DR SMR; G3QMM4; -.
DR STRING; 9593.ENSGGOP00000003766; -.
DR Ensembl; ENSGGOT00000003856.3; ENSGGOP00000003766.3; ENSGGOG00000003836.3.
DR GeneID; 101132582; -.
DR KEGG; ggo:101132582; -.
DR CTD; 56180; -.
DR eggNOG; KOG0439; Eukaryota.
DR GeneTree; ENSGT00940000155266; -.
DR HOGENOM; CLU_088040_0_0_1; -.
DR InParanoid; G3QMM4; -.
DR OMA; NARHTHK; -.
DR OrthoDB; 4837153at2759; -.
DR TreeFam; TF319778; -.
DR Proteomes; UP000001519; Chromosome X.
DR Bgee; ENSGGOG00000003836; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR039283; MOSPD1/3.
DR InterPro; IPR000535; MSP_dom.
DR InterPro; IPR008962; PapD-like_sf.
DR PANTHER; PTHR34441; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR34441:SF2; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00635; Motile_Sperm; 1.
DR SUPFAM; SSF49354; PapD-like; 1.
DR PROSITE; PS50202; MSP; 1.
PE 4: Predicted;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 160..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..143
FT /note="MSP"
FT /evidence="ECO:0000259|PROSITE:PS50202"
SQ SEQUENCE 213 AA; 24086 MW; 2E0944F48058B47F CRC64;
MHQQKRQPEL VEGNLPVFVF PTELIFYADD QSTHKQVLTL YNPYEFALKF KVLCTTPNKY
VVVDAAGAVK PQCCVDIVIR HRDVRSCHYG VIDKFRLQVS EQSQRKALGR KEVVATLLPS
AKEQQKEEEE KRLKEHLTES LFFEQSFQPE NRAVSSGPSL LTVFLGVVCI AALMLPTLGD
VESLVPLYLH LSVNQKLVAA YILGLITMAI LRT
//
