ID G3QRF6_GORGO Unreviewed; 210 AA.
AC G3QRF6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Syntaxin binding protein 6 {ECO:0000313|Ensembl:ENSGGOP00000005208.2};
GN Name=STXBP6 {ECO:0000313|Ensembl:ENSGGOP00000005208.2};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000005208.2, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000005208.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000005208.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000005208.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030091798; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004055085.1; XM_004055037.2.
DR RefSeq; XP_018865778.1; XM_019010233.1.
DR AlphaFoldDB; G3QRF6; -.
DR SMR; G3QRF6; -.
DR STRING; 9593.ENSGGOP00000005208; -.
DR Ensembl; ENSGGOT00000005344.3; ENSGGOP00000005208.2; ENSGGOG00000005321.3.
DR GeneID; 101134195; -.
DR KEGG; ggo:101134195; -.
DR CTD; 29091; -.
DR eggNOG; KOG1983; Eukaryota.
DR GeneTree; ENSGT00940000156499; -.
DR HOGENOM; CLU_101413_0_0_1; -.
DR InParanoid; G3QRF6; -.
DR OMA; TCQRYLP; -.
DR OrthoDB; 4297246at2759; -.
DR Proteomes; UP000001519; Chromosome 14.
DR Bgee; ENSGGOG00000005321; Expressed in heart and 5 other cell types or tissues.
DR GO; GO:0035542; P:regulation of SNARE complex assembly; IEA:InterPro.
DR GO; GO:0035493; P:SNARE complex assembly; IEA:Ensembl.
DR CDD; cd14681; PH-STXBP6; 1.
DR CDD; cd15892; R-SNARE_STXBP6; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR Gene3D; 2.30.29.90; -; 1.
DR InterPro; IPR028258; Sec3-PIP2_bind.
DR InterPro; IPR037821; STXBP6_PH.
DR InterPro; IPR037822; STXBP6_SNARE.
DR InterPro; IPR042855; V_SNARE_CC.
DR PANTHER; PTHR16092:SF14; EXOCYST COMPLEX COMPONENT 1 ISOFORM X1; 1.
DR PANTHER; PTHR16092; SEC3/SYNTAXIN-RELATED; 1.
DR Pfam; PF15277; Sec3-PIP2_bind; 1.
DR Pfam; PF00957; Synaptobrevin; 1.
DR SMART; SM01313; Sec3-PIP2_bind; 1.
DR SUPFAM; SSF58038; SNARE fusion complex; 1.
DR PROSITE; PS50892; V_SNARE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU00290};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT DOMAIN 151..210
FT /note="V-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50892"
SQ SEQUENCE 210 AA; 23554 MW; 7C046A90D4C4B2D8 CRC64;
MSAKSAISKE IFAPLDERML GAVQVKRRTK KKIPFLATGG QGEYLTYICL SVTNKKPTQA
SITKVKQFEG STSFVRRSQW MLEQLRQVNG IDPNGDSAEF DLLFENAFDQ WVASTASEKC
TFFQILHHTC QRYLTDRKPE FINCQSKIMG GNSILHSAAD SVTSAVQKAS QALNERGERL
GRAEEKTEDL KNSAQQFAET AHKLAMKHKC
//
