ID G3QRS1_GORGO Unreviewed; 575 AA.
AC G3QRS1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Scavenger receptor cysteine rich family member with 4 domains {ECO:0000313|Ensembl:ENSGGOP00000005334.2};
GN Name=SSC4D {ECO:0000313|Ensembl:ENSGGOP00000005334.2};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000005334.2, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000005334.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000005334.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000005334.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030052898; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004045670.1; XM_004045622.2.
DR AlphaFoldDB; G3QRS1; -.
DR STRING; 9593.ENSGGOP00000005334; -.
DR Ensembl; ENSGGOT00000005475.3; ENSGGOP00000005334.2; ENSGGOG00000005447.3.
DR GeneID; 101141154; -.
DR KEGG; ggo:101141154; -.
DR CTD; 136853; -.
DR eggNOG; ENOG502QU9F; Eukaryota.
DR GeneTree; ENSGT00940000160521; -.
DR HOGENOM; CLU_002555_11_2_1; -.
DR InParanoid; G3QRS1; -.
DR OMA; DEKGWGW; -.
DR OrthoDB; 5292724at2759; -.
DR TreeFam; TF329295; -.
DR Proteomes; UP000001519; Chromosome 7.
DR Bgee; ENSGGOG00000005447; Expressed in adult mammalian kidney and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR Gene3D; 3.10.250.10; SRCR-like domain; 4.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48071:SF15; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 4.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 4.
DR SUPFAM; SSF56487; SRCR-like; 4.
DR PROSITE; PS00420; SRCR_1; 4.
DR PROSITE; PS50287; SRCR_2; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT DOMAIN 58..158
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 189..289
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 344..444
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 473..573
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DISULFID 83..147
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 96..157
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 127..137
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 214..278
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 227..288
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 258..268
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 369..433
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 382..443
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 413..423
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 498..562
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 511..572
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 542..552
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 575 AA; 60841 MW; CA63DDDC5420F697 CRC64;
MHKEAEMLIG PQLDEKRWGW RLGDGSAAPP FLPQALSFLL LLPLASTLQP TPLPFQELRL
VGGPSRCQGR LEVMHGGSWG SVCDDDWDVV DANVVCRQLG CGLALPVPRP LAFGQGRGPI
LLDNVECRGQ EAALSECGSR GWGVHNCFHY EDVAVLCDEF LPTQPPTRKM LTSRAPPMTL
PNGKSEGSVR LVGGANLCQG RVEIMHSGLW GTVCDDDWGL PDAAVVCRQL GCGAAMAATT
NAFFGYGTGH ILLDNVHCEG GEPRLAACQS LGWGVHNCGH HEDAGALCAG LGPPTLTALP
SSATKEDWAW QTDPSATGVG PQPSRETALL TTAAWAAGKK SGRLRLVGGP GPCRGRVEVL
HAGGWGTVCD DDWDFADARV ACREAGCGPA LGATGLGHFG YGRGPVLLDN VGCAGTEARL
SDCFHLGWGQ HNCGHHEDAG ALCAGPEELG LQVQQDGSET TRVPTPRPRD GHLRLVNGAH
RCEGRVELYL GQRWGTVCDD AWDLRAAGVL CRQLGCGQAL AAPGEAHFGP GRGPILLDNV
KCRGEESALL LCSHIRWDAH NCDHSEDASV LCQPS
//
