ID G3QSY9_GORGO Unreviewed; 977 AA.
AC G3QSY9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=S1 RNA binding domain 1 {ECO:0000313|Ensembl:ENSGGOP00000005790.4};
GN Name=SRBD1 {ECO:0000313|Ensembl:ENSGGOP00000005790.4};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000005790.4, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000005790.4, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000005790.4, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000005790.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030013062; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030013063; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030013064; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030013065; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030013066; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030013067; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G3QSY9; -.
DR STRING; 9593.ENSGGOP00000005790; -.
DR Ensembl; ENSGGOT00000005943.4; ENSGGOP00000005790.4; ENSGGOG00000005910.4.
DR eggNOG; KOG1857; Eukaryota.
DR GeneTree; ENSGT00510000047850; -.
DR HOGENOM; CLU_009833_1_0_1; -.
DR InParanoid; G3QSY9; -.
DR OMA; RWAWRTR; -.
DR TreeFam; TF313600; -.
DR Proteomes; UP000001519; Chromosome 2A.
DR Bgee; ENSGGOG00000005910; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR CDD; cd05685; S1_Tex; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 1.10.10.650; RuvA domain 2-like; 1.
DR Gene3D; 1.10.3500.10; Tex N-terminal region-like; 1.
DR Gene3D; 1.10.150.310; Tex RuvX-like domain-like; 1.
DR Gene3D; 3.30.420.140; YqgF/RNase H-like domain; 1.
DR InterPro; IPR041692; HHH_9.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR003029; S1_domain.
DR InterPro; IPR044146; S1_Tex.
DR InterPro; IPR023323; Tex-like_dom_sf.
DR InterPro; IPR023319; Tex-like_HTH_dom_sf.
DR InterPro; IPR018974; Tex-like_N.
DR InterPro; IPR032639; Tex_YqgF.
DR InterPro; IPR006641; YqgF/RNaseH-like_dom.
DR InterPro; IPR037027; YqgF/RNaseH-like_dom_sf.
DR PANTHER; PTHR10724; 30S RIBOSOMAL PROTEIN S1; 1.
DR PANTHER; PTHR10724:SF10; S1 RNA-BINDING DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF12836; HHH_3; 1.
DR Pfam; PF17674; HHH_9; 1.
DR Pfam; PF00575; S1; 1.
DR Pfam; PF09371; Tex_N; 1.
DR Pfam; PF16921; Tex_YqgF; 1.
DR SMART; SM00316; S1; 1.
DR SMART; SM00732; YqgFc; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 2.
DR SUPFAM; SSF158832; Tex N-terminal region-like; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT DOMAIN 901..974
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 115..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 243..270
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..146
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 977 AA; 109864 MW; CCAC23E7AD6CB2D4 CRC64;
ESLEPRRWRL SSASEEDDKE DSAWEPQKKV PRSRKQPPPK ESKPKRMPRV KKNAPQISDG
SEVVVVKEEL SSSVAIADTA LEDRKNKLDT VQTLKTAKTK QKCAVQPHTV RRTKKLKVEE
TSKASNLEGE SNSSETPSTS TVWGGTCKKE ENDDDFTFGQ SPLKKIKTET CPQGQPVKFP
ANANNIKEEV EMNWDMVQVL SERTNIEPWV CANIIRLFND DNTIPFIIRY RKELINNLDA
DSLREVQQTL EELRAVAKKV HSTIQKIKKE GKMSECLLKA MLNCKTFEEL EHVSAPYKTG
SKGTKAQRAR QLGLEGAARA LLEKPGELSL LSYIRPDVKG LSTLQDIEIG VQHILADMIA
KDKDTLDFIR NLCQKRHVCI QSSLAKVSSK KVNEKDVDKF LLYQHFSCNI RNIHHHQILA
INRGENLKVL TVKVNISDGV KDEFCRWCIQ NRWRPRSFAR PELMKILYNS LNDSFKRLIY
PLLCRELRAK LTSDAEKESV MMFGRNLRQL LLTSPVPGRT LMGVDPGYKH GCKLAIISPT
SQILHTDVVY LHCGQGFREA EKIKTLLLNF NCSTVVIGNG TACRETEAYF ADLIMKNYFA
PLDVVYCIVS EAGASIYSVS PEANKEMPGL DPNLRSAVSI ARRVQDPLAE LVKIEPKHIG
VGMYQHDVSQ TLLKATLDSV VEECVSFVGV DINICSEVLL RHIAGLNANR AKNIIEWREK
NGPFINREQL KKVKGLGPKS FQQCAGFIRI NQDYIRTFCS QQTETSGQIQ GVAVTSSADV
EVTNEKQGKK KSKTAVNVLL KPNPLDQTCI HPESYDIAMR FLSSIGGTLY EIGKPEMQQK
INSFLEKEGM EKIAERLQTT VHTLQVIIDG LSQPESFDFR TDFDKPDFKR SIVCLEDLQV
GTVLTGKVEN ATLFGIFVDI GVGKSGLIPI RNVTEAKLSK TKKRRSLGLG PGERVEVQVL
NIDIPRSRIT LDLIRVL
//
