ID G3R1F9_GORGO Unreviewed; 635 AA.
AC G3R1F9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Tripartite motif containing 47 {ECO:0000313|Ensembl:ENSGGOP00000009027.3};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000009027.3, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000009027.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000009027.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000009027.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030036031; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004041074.2; XM_004041026.2.
DR AlphaFoldDB; G3R1F9; -.
DR STRING; 9593.ENSGGOP00000009027; -.
DR Ensembl; ENSGGOT00000009277.3; ENSGGOP00000009027.3; ENSGGOG00000009236.3.
DR GeneID; 101143823; -.
DR KEGG; ggo:101143823; -.
DR CTD; 91107; -.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000154334; -.
DR InParanoid; G3R1F9; -.
DR OMA; CLESRDY; -.
DR OrthoDB; 5322335at2759; -.
DR TreeFam; TF351086; -.
DR Proteomes; UP000001519; Chromosome 5.
DR Bgee; ENSGGOG00000009236; Expressed in adult mammalian kidney and 6 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:Ensembl.
DR CDD; cd19842; Bbox1_TRIM25-like_C-IV; 1.
DR CDD; cd19769; Bbox2_TRIM16-like; 1.
DR CDD; cd16604; RING-HC_TRIM47-like_C-IV; 1.
DR CDD; cd15808; SPRY_PRY_TRIM47; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR042780; TRIM47_SPRY_PRY.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF21; E3 UBIQUITIN-PROTEIN LIGASE TRIM47; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 9..55
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 174..214
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 407..628
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 76..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..114
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 635 AA; 69226 MW; F9F0A6243C5D1F8F CRC64;
MDGSGPFSCP ICLEPLREPV TLPCGHNFCL ACLGALWPHR GAGGPGGAAR CPLCQEPFPD
GLQLRKNHTL SELLQLRQGS GPGPGPGPAP ALAPEPSAPS APPSAPEPSA PCAPEPWPAG
EEPVRCDACP EGAALPAALS CLSCLASFCP AHLGPHERSP ALRGHRLVPP LRRLEESLCP
RHLRPLERYC RAERVCLCEA CAAQEHRGHE LVPLEQERAL QEAEQSKVLS AVEDRMDELG
AGIAQSRRTV ALIKSAAVAE RERVSRLFAD AAAALQGFQT QVLGFIEEGE AAMLGCSQGD
LRRQEEQRSR LSRVRQNLSQ VPEADSVSFL QELLALRLAL EDGCGPGPGP PRELSFTKSS
QAVRAVRDML AVACVNQWEQ LRGPGGNEDG PQKLDSEADA EPQDLESTNL LESEAPRDYF
LKFAYIVDLD SDTADKFLQL FGTKGVKRVL CPINYPLSPT RFTHCEQVLG EGALDRGTYY
WEVEIIEGWV SVGVMAEDFS PQEPYDRGRL GRNAHSCCLQ WNGRSFSVWF HGLEAPLPHP
FSPTVGVCLE YADRALAFYA VRDGKMSLLR RLKASRPRRG GIPASPIDPF QSRLDSHFAG
LFTHRLKPAF FLESVDAHLQ IGPLKKSCIS VLKRR
//
