ID G3RDH9_GORGO Unreviewed; 438 AA.
AC G3RDH9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Coiled-coil domain containing 78 {ECO:0000313|Ensembl:ENSGGOP00000013584.3};
GN Name=CCDC78 {ECO:0000313|Ensembl:ENSGGOP00000013584.3};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000013584.3, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000013584.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000013584.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000013584.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030098289; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004056946.1; XM_004056898.2.
DR AlphaFoldDB; G3RDH9; -.
DR STRING; 9593.ENSGGOP00000013584; -.
DR Ensembl; ENSGGOT00000013975.3; ENSGGOP00000013584.3; ENSGGOG00000013922.3.
DR eggNOG; ENOG502SNR6; Eukaryota.
DR GeneTree; ENSGT00390000013678; -.
DR HOGENOM; CLU_032909_0_0_1; -.
DR InParanoid; G3RDH9; -.
DR OMA; WAGTSKK; -.
DR TreeFam; TF336362; -.
DR Proteomes; UP000001519; Chromosome 16.
DR Bgee; ENSGGOG00000013922; Expressed in cerebellum and 5 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR InterPro; IPR039873; CCDC78.
DR InterPro; IPR029329; DUF4472.
DR PANTHER; PTHR22106; COILED-COIL DOMAIN-CONTAINING PROTEIN 78; 1.
DR PANTHER; PTHR22106:SF5; COILED-COIL DOMAIN-CONTAINING PROTEIN 78; 1.
DR Pfam; PF14739; DUF4472; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT DOMAIN 56..164
FT /note="DUF4472"
FT /evidence="ECO:0000259|Pfam:PF14739"
FT REGION 109..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 76..103
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 173..242
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 121..141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 438 AA; 48521 MW; DECB3FCF12154A24 CRC64;
MEHAATTGPR PGPPSRRVEN VVLRAKDWLP GAPGGTAVWA TSLEAEVPPD LALNKEQQLQ
ISKELVDIQI TTHHLQEQHE AEIFQLKSEI LQLESRVLEL ELRGDGASQG CAVPVESDPR
HPRAPAQELR HKAQVPGHSD DRRFQVQPKN AMNPENEQHR LGSSLQGEVK RALERQEARQ
QALEMRVATL GRQLQVARKE ARAAGQRLAT QAVVLCSCQG QLRQAEAENA RLQLQLKKLK
DEYVLRLQHC AREAVEHADG AGQTPATMAL RTFLEATLED IRAAHRSREQ QLARAARSYH
KRLVDLSRRH EELLVAYRAP GNPQAIFDIA SLDLEPLPVP LVTDFSHRED QHGGPGALLS
SPKKGPGGAS QGGTSEPQGL DAASWAQIHQ KLRDFSRSTQ SWNGSGHSCW SGPRWLKSNF
LSYRSTWTST WAGTSTKS
//
