ID G3RJM5_GORGO Unreviewed; 305 AA.
AC G3RJM5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=N-acetylglucosamine-1-phosphate transferase subunit gamma {ECO:0000313|Ensembl:ENSGGOP00000015920.2};
GN Name=GNPTG {ECO:0000313|Ensembl:ENSGGOP00000015920.2};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000015920.2, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000015920.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000015920.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000015920.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030098346; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004056982.1; XM_004056934.2.
DR AlphaFoldDB; G3RJM5; -.
DR STRING; 9593.ENSGGOP00000015920; -.
DR Ensembl; ENSGGOT00000016374.3; ENSGGOP00000015920.2; ENSGGOG00000016320.3.
DR GeneID; 101144934; -.
DR KEGG; ggo:101144934; -.
DR CTD; 84572; -.
DR eggNOG; KOG2397; Eukaryota.
DR GeneTree; ENSGT00510000048359; -.
DR HOGENOM; CLU_075705_0_0_1; -.
DR InParanoid; G3RJM5; -.
DR OMA; CGSKNRQ; -.
DR OrthoDB; 2916989at2759; -.
DR TreeFam; TF329550; -.
DR Proteomes; UP000001519; Chromosome 16.
DR Bgee; ENSGGOG00000016320; Expressed in cerebellum and 5 other cell types or tissues.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0070622; C:UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex; IEA:Ensembl.
DR GO; GO:0046835; P:carbohydrate phosphorylation; IEA:Ensembl.
DR Gene3D; 2.70.130.10; Mannose-6-phosphate receptor binding domain; 1.
DR InterPro; IPR010506; DMAP1-bd.
DR InterPro; IPR039794; Gtb1-like.
DR InterPro; IPR009011; Man6P_isomerase_rcpt-bd_dom_sf.
DR InterPro; IPR044865; MRH_dom.
DR InterPro; IPR012913; OS9-like_dom.
DR PANTHER; PTHR12630:SF6; N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNIT GAMMA; 1.
DR PANTHER; PTHR12630; N-LINKED OLIGOSACCHARIDE PROCESSING; 1.
DR Pfam; PF07915; PRKCSH; 1.
DR SMART; SM01137; DMAP_binding; 1.
DR SUPFAM; SSF50911; Mannose 6-phosphate receptor domain; 1.
DR PROSITE; PS51912; DMAP1_BIND; 1.
DR PROSITE; PS51914; MRH; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..305
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003452693"
FT DOMAIN 69..171
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 176..279
FT /note="DMAP1-binding"
FT /evidence="ECO:0000259|PROSITE:PS51912"
FT REGION 268..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..292
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 305 AA; 34130 MW; 9D9CF0603E508323 CRC64;
MAVGLARLLV LLGLSARGPA PAGAAKMKVV EEPNTFGVNN PFLPQASRLQ AKRDPSPVSG
PVHLFRLSGK CFSLVESTYK YEFCPFHNVT QHEQTFRWNA YSGILGIWHE WEIANNTFTG
MWMRDGDACR SRSRQSKVEL ACGKSNRLAH VSEPSTCVYA LTFETPLVCH PHALLVYPTL
PEALQRQWDQ VEQDLADELI TPQGHEKLLR TLFEDAGYLK TPEEKEPTQL EGGPDSLGFE
TLENCRKAHK ELSKEIKRLK GLLTQHGIPY TRPTETSNLE HLGHKTPRAK SPEQLRGDPG
LRGSL
//
