ID G3RR85_GORGO Unreviewed; 107 AA.
AC G3RR85;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=SH3 domain-binding glutamic acid-rich-like protein {ECO:0000256|PIRNR:PIRNR008142};
GN Name=SH3BGRL2 {ECO:0000313|Ensembl:ENSGGOP00000018309.2};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000018309.2, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000018309.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000018309.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000018309.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SH3BGR family.
CC {ECO:0000256|ARBA:ARBA00007764, ECO:0000256|PIRNR:PIRNR008142}.
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DR EMBL; CABD030046218; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030046219; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030046220; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004044371.1; XM_004044323.2.
DR AlphaFoldDB; G3RR85; -.
DR SMR; G3RR85; -.
DR Ensembl; ENSGGOT00000030499.2; ENSGGOP00000018309.2; ENSGGOG00000027182.2.
DR GeneID; 101127865; -.
DR KEGG; ggo:101127865; -.
DR CTD; 83699; -.
DR GeneTree; ENSGT00940000159157; -.
DR HOGENOM; CLU_084862_3_0_1; -.
DR InParanoid; G3RR85; -.
DR OMA; MYKNIPK; -.
DR OrthoDB; 4265519at2759; -.
DR Proteomes; UP000001519; Chromosome 6.
DR Bgee; ENSGGOG00000027182; Expressed in frontal cortex and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0031965; C:nuclear membrane; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
DR CDD; cd03030; GRX_SH3BGR; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR006993; Glut_rich_SH3-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR12232; SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN; 1.
DR PANTHER; PTHR12232:SF4; SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 2; 1.
DR Pfam; PF04908; SH3BGR; 1.
DR PIRSF; PIRSF008142; SH3-bind_E-rich_L; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW SH3-binding {ECO:0000256|ARBA:ARBA00023036}.
SQ SEQUENCE 107 AA; 12326 MW; D160736103FA8635 CRC64;
MVIRVFIASS SGFVAIKKKQ QDVVRFLEAN KIEFEEVDIT MSEEQRQWMY KNVPPEKKPT
QGNPLPPQIF NGDRYCGDYD SFFESKESNT VFSFLGLKPR LASKAEP
//
