ID G3S0T9_GORGO Unreviewed; 583 AA.
AC G3S0T9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Kelch like family member 35 {ECO:0000313|Ensembl:ENSGGOP00000021684.2};
GN Name=KLHL35 {ECO:0000313|Ensembl:ENSGGOP00000021684.2};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000021684.2, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000021684.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000021684.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000021684.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030080262; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004051873.1; XM_004051825.2.
DR AlphaFoldDB; G3S0T9; -.
DR STRING; 9593.ENSGGOP00000021684; -.
DR Ensembl; ENSGGOT00000025718.2; ENSGGOP00000021684.2; ENSGGOG00000015839.3.
DR GeneID; 101152575; -.
DR KEGG; ggo:101152575; -.
DR CTD; 283212; -.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000161093; -.
DR InParanoid; G3S0T9; -.
DR OMA; ESEPGCE; -.
DR OrthoDB; 5472491at2759; -.
DR TreeFam; TF351654; -.
DR Proteomes; UP000001519; Chromosome 11.
DR Bgee; ENSGGOG00000015839; Expressed in testis and 3 other cell types or tissues.
DR CDD; cd18265; BTB_POZ_KLHL35; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR030601; KLHL35_BTB_POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR PANTHER; PTHR24412:SF187; KELCH-LIKE PROTEIN 35; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 4.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 41..119
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 583 AA; 63011 MW; 01920CE31CC91CFE CRC64;
MRQGHRPEES EPGCEAPCAG PCHAQRVLQT LNAYRRSGTL TDVVLRAGGR DFPCHRAALS
AGSAYFRSLF AAGRPERGPA VVPVVPVAPE APGTSPAGTA AALAVVLDYV YGAGVRLRAE
DEAAAVLALA ERLGVAGLRE ACVRFLEGRL RAANSLALRR VAAAFSLAPL AERCGRVLRQ
AFAEVARHAD FLELAPDEVA ALLADPALGV AREEAVFEAA MRWVRHDAPA RRGQLRRLLE
HVRLPLLAPA YFLEKVEADE LLQACGECRP LLLEARACFI LGREAGALRT RPRRFMDLAE
VIVVIGGCDR KGLLKLPFAD AYHPESQRWT PLPSLPGYTR SEFAACALRN DVYVSGGHIN
SHDVWMFSSH LHTWIKVASL HKGRWRHKMA VVQGQLFAVG GFDGLRRLHS VERYDPFSNT
WAAAAPLPEA VSSAAVASCA GKLFVIGGAR QGGVNTDKVQ CFDPKEDRWS LRSPAPFSQR
CLEAVSLEDT IYVMGGLMSK IFTYDPGTDV WGEAAVLPSP VESCGVTVCD GKVHILGGWD
DRGESTDKVF TFDPSSGQVE AQPSLQRCTS SHGCVTIIQS LGR
//
