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Database: UniProt
Entry: G3S2H4_GORGO
LinkDB: G3S2H4_GORGO
Original site: G3S2H4_GORGO 
ID   G3S2H4_GORGO            Unreviewed;       265 AA.
AC   G3S2H4;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   05-JUN-2019, entry version 41.
DE   SubName: Full=Ras association domain family member 5 {ECO:0000313|Ensembl:ENSGGOP00000022272};
GN   Name=RASSF5 {ECO:0000313|Ensembl:ENSGGOP00000022272};
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Gorilla.
OX   NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000022272, ECO:0000313|Proteomes:UP000001519};
RN   [1] {ECO:0000313|Ensembl:ENSGGOP00000022272, ECO:0000313|Proteomes:UP000001519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Scally A.;
RT   "Insights into the evolution of the great apes provided by the gorilla
RT   genome.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGGOP00000022272}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSGGOP00000022272}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22398555; DOI=10.1038/nature10842;
RA   Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA   Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA   McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C.,
RA   Xue Y., Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V.,
RA   Beal K., Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A.,
RA   Gu Y., Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K.,
RA   Lunter G., Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D.,
RA   Phillips A.D., Prado-Martinez J., Rogers A.S., Sajjadian S.,
RA   Schmidt D., Shaw K., Simpson J.T., Stenson P.D., Turner D.J.,
RA   Vigilant L., Vilella A.J., Whitener W., Zhu B., Cooper D.N.,
RA   de Jong P., Dermitzakis E.T., Eichler E.E., Flicek P., Goldman N.,
RA   Mundy N.I., Ning Z., Odom D.T., Ponting C.P., Quail M.A., Ryder O.A.,
RA   Searle S.M., Warren W.C., Wilson R.K., Schierup M.H., Rogers J.,
RA   Tyler-Smith C., Durbin R.;
RT   "Insights into hominid evolution from the gorilla genome sequence.";
RL   Nature 483:169-175(2012).
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DR   EMBL; CABD030008535; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CABD030008536; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CABD030008537; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_004028331.1; XM_004028282.2.
DR   SMR; G3S2H4; -.
DR   Ensembl; ENSGGOT00000030104; ENSGGOP00000022272; ENSGGOG00000015265.
DR   GeneID; 101128172; -.
DR   KEGG; ggo:101128172; -.
DR   CTD; 83593; -.
DR   GeneTree; ENSGT00940000159288; -.
DR   KO; K08015; -.
DR   OrthoDB; 1120975at2759; -.
DR   Proteomes; UP000001519; Chromosome 1.
DR   Bgee; ENSGGOG00000015265; Expressed in 6 organ(s), highest expression level in prefrontal cortex.
DR   GO; GO:0017016; F:Ras GTPase binding; IEA:InterPro.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   InterPro; IPR033614; C-RASSF.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR033623; RASSF5.
DR   InterPro; IPR011524; SARAH_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR22738; PTHR22738; 1.
DR   PANTHER; PTHR22738:SF9; PTHR22738:SF9; 1.
DR   Pfam; PF16517; Nore1-SARAH; 1.
DR   Pfam; PF00788; RA; 1.
DR   SMART; SM00314; RA; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   PROSITE; PS50200; RA; 1.
DR   PROSITE; PS50951; SARAH; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001519};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT   DOMAIN      121    211       Ras-associating. {ECO:0000259|PROSITE:
FT                                PS50200}.
FT   DOMAIN      213    260       SARAH. {ECO:0000259|PROSITE:PS50951}.
FT   COILED      232    259       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   265 AA;  30359 MW;  66AD5D84EFA6D6CB CRC64;
     MTVDSSMSSG YCSLDEELED CFFTAKTTFF RNAQSKHLSK NVCKPVEETQ RPPTLQEIKQ
     KIDSYNTREK NCLGMKLSED GTYTGFIKVH LKLRRPVTVP AGIRPQSIYD AIKEVNLAAT
     TDKRTSFYLP LDAIKQLHIS STTTVSEVIQ GLLKKFMVVD NPQKFALFKR IHKDGQVLFQ
     KLSIADRPLY LRLLAGPDTE VLSFVLKENE TGEVEWDAFS IPELQNFLTI LEKEEQDKIQ
     QVQKKYDKFR QKLEEALRES QGKPG
//
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