ID G3S6K9_GORGO Unreviewed; 180 AA.
AC G3S6K9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Nuclear nucleic acid-binding protein C1D {ECO:0000256|ARBA:ARBA00015212, ECO:0000256|RuleBase:RU368003};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000023716.2, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000023716.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000023716.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000023716.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Plays a role in the recruitment of the exosome to pre-rRNA to
CC mediate the 3'-5' end processing of the 5.8S rRNA.
CC {ECO:0000256|RuleBase:RU368003}.
CC -!- SUBUNIT: Monomer and homodimer. {ECO:0000256|RuleBase:RU368003}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU368003}.
CC Nucleus, nucleolus {ECO:0000256|RuleBase:RU368003}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU368003}.
CC -!- SIMILARITY: Belongs to the C1D family. {ECO:0000256|ARBA:ARBA00009154,
CC ECO:0000256|RuleBase:RU368003}.
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DR EMBL; CABD030012330; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_018877131.1; XM_019021586.1.
DR AlphaFoldDB; G3S6K9; -.
DR STRING; 9593.ENSGGOP00000023716; -.
DR Ensembl; ENSGGOT00000022058.2; ENSGGOP00000023716.2; ENSGGOG00000025982.2.
DR GeneTree; ENSGT00390000015405; -.
DR HOGENOM; CLU_064339_4_1_1; -.
DR InParanoid; G3S6K9; -.
DR OMA; NNMEEYP; -.
DR Proteomes; UP000001519; Chromosome 2A.
DR Bgee; ENSGGOG00000025982; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000178; C:exosome (RNase complex); IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0000460; P:maturation of 5.8S rRNA; IBA:GO_Central.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR InterPro; IPR011082; Exosome-assoc_fac/DNA_repair.
DR InterPro; IPR007146; Sas10/Utp3/C1D.
DR PANTHER; PTHR15341:SF3; NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D; 1.
DR PANTHER; PTHR15341; SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR; 1.
DR Pfam; PF04000; Sas10_Utp3; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU368003};
KW DNA-binding {ECO:0000256|RuleBase:RU368003};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU368003};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU368003};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552,
KW ECO:0000256|RuleBase:RU368003}.
SQ SEQUENCE 180 AA; 20212 MW; 3FB04111F48E6D4D CRC64;
MPSPSVSTSA ASVLEGVCGR ARSTYRTREE GEEQSWSAIM AGEEINEDYP VEIHEYLSAF
ENSIGAVDEM LKTMMSVSRN ELLQKLDPLE QAKVDLVSAY TLNSMFWVYL ATQGVNPKEH
PVKQELERIR VYMNRVKEIT DKKKAGKLDR GAASRFVKNA LWEPKPKNAS KVANKGKSKN
//
