ID G3SA18_GORGO Unreviewed; 639 AA.
AC G3SA18;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Selenoprotein O {ECO:0000256|ARBA:ARBA00031547};
GN Name=SELENOO {ECO:0000313|Ensembl:ENSGGOP00000024939.2};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000024939.2, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000024939.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000024939.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000024939.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the SELO family.
CC {ECO:0000256|ARBA:ARBA00009747}.
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DR EMBL; CABD030121837; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030121838; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G3SA18; -.
DR STRING; 9593.ENSGGOP00000024939; -.
DR Ensembl; ENSGGOT00000024624.2; ENSGGOP00000024939.2; ENSGGOG00000014406.3.
DR GeneTree; ENSGT00390000005508; -.
DR HOGENOM; CLU_010245_4_0_1; -.
DR InParanoid; G3SA18; -.
DR OMA; ELCVTXS; -.
DR Proteomes; UP000001519; Chromosome 22.
DR Bgee; ENSGGOG00000014406; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0005694; C:chromosome; IEA:Ensembl.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0070733; F:AMPylase activity; IEA:Ensembl.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR HAMAP; MF_00692; SelO; 1.
DR InterPro; IPR003846; SelO.
DR PANTHER; PTHR12153:SF15; PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12153; SELENOPROTEIN O; 1.
DR Pfam; PF02696; SelO; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 30..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 607..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..45
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 639 AA; 70499 MW; 6BDA1E5D4944B466 CRC64;
RSTLSGAAME PAPRWLAGLR FDNRALRALP VEAPPPGPEG APSAPRPVPG ACFTRVQPTP
LRQPRLVALS EPALALLGLG APPAREAEAE AEAALFFSGN ALLPGAEPAA HCYCGHQFGQ
FAGQLGDGAA MYLGEVCTAT GERWELQLKG AGPTPFSRQA DGRKVLRSSI REFLCSEAMF
HLGVPTTRAG ACVTSQSMVV RDVFYDGNPK YEQCTVVLRV ASTFIRFGSF EIFKSADEHT
GRAGPSVGRN DIRVQLLDYV ISSFYPEIQA AHASDSVQRN AAFFREVTRR TARMVAEWQC
VGFCHGVLNT DNMSILGLTI DYGPFGFLDR YDPDHVCNAS DNTGRYAYSK QPEVCRWNLR
KLAEALQPEL PLELGEAILA EEFDAEFQRH YLQKMRRKLG LVQVELEEDG ALVSKLLETM
HLTGADFTNT FYLLSSFPVE AESPGLAEFL ARLMEQCASL EELRLAFRPQ MDPRQLSMML
MLAQSNPQLF ALMGTRAGIA RELERVEQQS QLEQLSAAEL QSRNHGHWAD WLQAYRARLD
KDLEGAGDAA AWQAEHVRVM HANNPKYVLR NYIAQNAIEA AERGDFSEVR RVLKLLETPY
HCEAGAATDA EATEANGADS RQRSYSSKPP LWAAELCVT
//
