ID G3SJZ3_GORGO Unreviewed; 594 AA.
AC G3SJZ3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=AT-rich interaction domain 5A {ECO:0000313|Ensembl:ENSGGOP00000028436.2};
GN Name=ARID5A {ECO:0000313|Ensembl:ENSGGOP00000028436.2};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000028436.2, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000028436.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000028436.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000028436.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030010336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030010337; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030010338; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030010339; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004031482.1; XM_004031434.2.
DR AlphaFoldDB; G3SJZ3; -.
DR STRING; 9593.ENSGGOP00000028436; -.
DR Ensembl; ENSGGOT00000028508.2; ENSGGOP00000028436.2; ENSGGOG00000017068.3.
DR GeneID; 101126944; -.
DR KEGG; ggo:101126944; -.
DR CTD; 10865; -.
DR GeneTree; ENSGT00940000161253; -.
DR InParanoid; G3SJZ3; -.
DR OMA; DQMVPGK; -.
DR OrthoDB; 445024at2759; -.
DR Proteomes; UP000001519; Chromosome 2A.
DR Bgee; ENSGGOG00000017068; Expressed in heart and 5 other cell types or tissues.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0050681; F:nuclear androgen receptor binding; IEA:Ensembl.
DR GO; GO:0030331; F:nuclear estrogen receptor binding; IEA:Ensembl.
DR GO; GO:0046965; F:nuclear retinoid X receptor binding; IEA:Ensembl.
DR GO; GO:0046966; F:nuclear thyroid hormone receptor binding; IEA:Ensembl.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR GO; GO:0071391; P:cellular response to estrogen stimulus; IEA:Ensembl.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd16884; ARID_ARID5A; 1.
DR Gene3D; 1.10.150.60; ARID DNA-binding domain; 1.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR PANTHER; PTHR13964:SF25; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 5A; 1.
DR PANTHER; PTHR13964; RBP-RELATED; 1.
DR Pfam; PF01388; ARID; 1.
DR SMART; SM01014; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SUPFAM; SSF46774; ARID-like; 1.
DR PROSITE; PS51011; ARID; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 55..147
FT /note="ARID"
FT /evidence="ECO:0000259|PROSITE:PS51011"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 146..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..193
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 594 AA; 64149 MW; 515B40BC12B534E0 CRC64;
MAAPVKGNRK QSTEGDALDP PASPKPAGEQ NRIQNPISLE DSPEAGGERE EEQEREEEQA
FLVSLYKFMK ERHTPIERVP HLGFKQINLW KIYKAVEKLG AYELVTGRRL WKNVYDELGG
SPGSTSAATC TRRHYERLVL PYVRHLKGED DKPLPTSKPR KQYKMAKENR GDDGATERPK
KAKEERRMDQ MMPGKTKADA ADPAPLPSQE PPRNSTEQQG LASGSSVSFV GASGCPEAYK
RLLSSFYCKG THGIMSPLAK KKLLAQVSKV EALQCQEEGC RHGAEPQASP ALHLPESPQS
PKGLTENSRH RLTPQEGLQA PGGSLREEAQ AGPCPAAPIF KGCFHTHPTE VLKPVSQHPR
DFFSRLKDGV LLGPPGKEGL SVKEPQLVWG GDANRPSAFH KGGSRKGILY PKPKACLVSP
MAKVPAESPM LPPTFPSSPG LGSKRSLEEE GAAHSGKRLR AVSPFLKEAD AKKCGAKPAG
SGLVSCLLGP ALGPVPPEAY RGTMLHCPLN FTGTPGPLKG QAALPFSPLV IPAFPAHFLA
TAGPSPMAAG LMHFPPTSFD STLRHRLCPA SSAWHAPPVT TYAAPHFFHL NTKL
//
