ID G3SWP8_LOXAF Unreviewed; 365 AA.
AC G3SWP8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Cell adhesion molecule 3 {ECO:0000313|Ensembl:ENSLAFP00000004766.3};
GN Name=CADM3 {ECO:0000313|Ensembl:ENSLAFP00000004766.3};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000004766.3, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000004766.3, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000004766.3,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000004766.3}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000004766.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3SWP8; -.
DR STRING; 9785.ENSLAFP00000004766; -.
DR Ensembl; ENSLAFT00000005682.3; ENSLAFP00000004766.3; ENSLAFG00000005683.3.
DR eggNOG; ENOG502QWJ8; Eukaryota.
DR GeneTree; ENSGT00940000159779; -.
DR HOGENOM; CLU_047574_1_0_1; -.
DR InParanoid; G3SWP8; -.
DR OMA; MTQERAL; -.
DR TreeFam; TF326804; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR45889:SF5; CELL ADHESION MOLECULE 3; 1.
DR PANTHER; PTHR45889; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 334..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..117
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 135..233
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 238..320
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 157..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..185
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 365 AA; 40242 MW; 6463A39CDA81AEF4 CRC64;
GYWQEQDLEL GTLAPLDEAI SSSVWSSPDM LASQDSQPWT SDETVVAGGT VELQCQVKDH
EDSSLQWSNP AQQTLYFGEK RALRDNRIQL VRSTPQELTI SISNVALADE GEYTCSIFTM
PVRTAKSLVT VLGIPQKPII SGYKSPLREN DQTTLNCRSS GSKPAAKLSW RKGDQELHGE
PTRAQEDPNG KTFTVSSSVT FQVTREDDGV NIVCSVNHES LQGAERSASQ RIEVLYTPTA
MIRPDPPHPR EGQKLLLHCE GHGNPVPKQY LWEKEGSVPP LKMTQERALI FPFLNKSDSG
TYGCTATSNM GSHKAYYTLN VNDPSPVPSS SSTYHAIIGG IVAFIVFLLL ILLIFLGHYL
IRHKG
//
