ID G3SXF2_LOXAF Unreviewed; 430 AA.
AC G3SXF2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Solute carrier family 38 member 8 {ECO:0000313|Ensembl:ENSLAFP00000005080.2};
GN Name=SLC38A8 {ECO:0000313|Ensembl:ENSLAFP00000005080.2};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000005080.2, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000005080.2, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000005080.2,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000005080.2}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000005080.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_003418131.1; XM_003418083.1.
DR AlphaFoldDB; G3SXF2; -.
DR STRING; 9785.ENSLAFP00000005080; -.
DR Ensembl; ENSLAFT00000006056.2; ENSLAFP00000005080.2; ENSLAFG00000006058.2.
DR GeneID; 100657567; -.
DR KEGG; lav:100657567; -.
DR CTD; 146167; -.
DR eggNOG; KOG1305; Eukaryota.
DR GeneTree; ENSGT00940000157764; -.
DR HOGENOM; CLU_038973_0_0_1; -.
DR InParanoid; G3SXF2; -.
DR OMA; CEACFIV; -.
DR OrthoDB; 131929at2759; -.
DR TreeFam; TF328787; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR013057; AA_transpt_TM.
DR PANTHER; PTHR22950; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR22950:SF226; SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 8-RELATED; 1.
DR Pfam; PF01490; Aa_trans; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..393
FT /note="Amino acid transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01490"
SQ SEQUENCE 430 AA; 46678 MW; 4B94F8574B81B75C CRC64;
MEGQTPGSRD LAEKSPLAAH PRSLSSLGAV FILMKSSLGA GLLNFPWAFY QAGGLAPAFL
VELVSMVFLI SGLLILGYAA SVSGQSTYQG VVRGLCGPSV GKLCEACFIV NLLMISVAFL
RVIGDQLEKL CDFLLPSMPL APQPWYTDQH FTLILLSILV ILPLSAPREI SFQKYTSILG
TLAACYLTLV IMVQYYLWPL GLVREPRVLQ SPSSWTSVFS VFPTICFGFQ CHEAAVSIYC
SMRNQRLSHW ALVSMLSLLP CCLIYSLTGA YGFLTFGAGV SADILMSYPG NDVVVIVARV
LFAVSIVTVY PIVLFLGRSV LQDFWRRSCC RALADPLGLG VRMPLTVSWV AVTLTMALLL
PDLSEVIGII GSISSFFIFI FPGLCLICAM DVEPLGPRLK CCLELWGVAS VLVGTFIFGQ
SMVVAVLELF
//
