ID G3SY97_LOXAF Unreviewed; 1264 AA.
AC G3SY97;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Zinc finger and BTB domain containing 40 {ECO:0000313|Ensembl:ENSLAFP00000005443.2};
GN Name=ZBTB40 {ECO:0000313|Ensembl:ENSLAFP00000005443.2};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000005443.2, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000005443.2, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000005443.2,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000005443.2}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000005443.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; G3SY97; -.
DR STRING; 9785.ENSLAFP00000005443; -.
DR Ensembl; ENSLAFT00000006484.2; ENSLAFP00000005443.2; ENSLAFG00000006483.2.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00930000151052; -.
DR InParanoid; G3SY97; -.
DR OMA; CHLLCSI; -.
DR TreeFam; TF350897; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0006974; P:DNA damage response; IEA:Ensembl.
DR CDD; cd18225; BTB_POZ_ZBTB40; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 10.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR030404; ZBTB40_BTB_POZ_dom.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24394:SF0; ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 40; 1.
DR PANTHER; PTHR24394; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR Pfam; PF12874; zf-met; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00355; ZnF_C2H2; 14.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 11.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 24..87
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 830..858
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 859..886
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 887..915
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 916..943
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 944..972
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 975..1003
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1003..1030
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1031..1053
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1071..1099
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1100..1128
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1160..1183
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 128..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 152..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 713..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 805..824
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 713..742
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1264 AA; 140966 MW; F73605ECD0341305 CRC64;
MELPNYSRQL LQQLYTLCKE QQFCDCTISI GSIYFRAHKL VLAAASLLFK TLLDNTDTIS
IDASVVSPEE FALLLEMMYT GKLPVGKHNF SKIISLADSL QMFDVAVSCK NLLTSLVNCS
IQGQVGRDVP VPSPESFRKE PEKPQVEILS SEGAGEPHVP LEGSAPPGGP VKAETEEAAQ
PVPQEPSVEP PTAQEMLRNA ETPAETPNSA EVCSPSPVVQ TFGEAMEAST EPEYERKRYQ
LDFLLENESI FSDALSVTQD VLKRLEECSE IKGPQKETMM ECLEAEEGHS AFQRILDKVR
DESMDVQTVV SLLRLYQDSN PAVKTALLAL SPLGSTEEGK TLSVLLLEHK EDLIRCVTQL
RPIMEFLETA KEEFLPGTEK RVILNCCEVG TPKETIENLL HRVTEEKTLT AESLVKLLQA
VKTTFPNLCL LLENLQKLAT LPSTTGLSDV TCEHPRSKRA QDASIKLTIM TSSVQPSTDD
YGTELLRRYH ENLSEIFTDN QMLLKVISHA KSVALEKDRE VMEKLVKQDS GSGGFSSLIS
AVLEKQTLSA TAVWQLLLVA QETKTCPLNL LMEEIQREPG ADAFFQTVTT PESAALETIL
RHKRLVIEAI QQKIDLKYFT SEEEPLAETV KQILSISSET ASPEASLRAV LSRAMEKSVS
AIEICHLLCS IHKWFPGLQP VMQELACIGF LAKEDGQKEM WKVSNKFHLE ANDKSDEKAA
EPAEEDCRAG KRNDEGETGS LPEQEKDTSA SPDSAKKSFV CKACDKSFHF YCRLKVHMKR
CRVAKSKQVQ CKDCSETKDS RKELEKHQLE AHGAGGEPDI PKKKKKRLPV TCDLCGREFA
HASGMQYHKL TEHFDEKPFS CEECGAKFAA NSTLKNHLRL HTGDRPFMCK HCLMTFTQAS
ALAYHTKKKH SEGKMYACQY CDAVFAQSIE LSRHVRTHTG DKPYVCRDCG KGFRQANGLS
IHLHTFHKPD IEDPYDCKKC RMSFPTLQDH RKHIHEVHSK EYHPCPTCGK IFSAPSMLER
HMVTHVGGKP FSCGICNKAY QQLSGLWYHN RTHHPDVFAA QNHRSSKFSS LQCSSCDKTF
PNTMEHKKHI KAEHADVKFH ECDKCKELFP TPALLQVHVK CQHSGSQPFR CLYCAATFRF
PGALQHHVTT EHFKQSENTF PCELCGELFT SQTQLDGHLE SEHPKVMGTE TQAAASPVVQ
VIQAPEPVAP AEQVITLEET QLAGSQVFVT LPDSQTSQTS SELVAVTVED LLDGTVTLIC
GEAK
//
