ID G3SZ24_LOXAF Unreviewed; 606 AA.
AC G3SZ24;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Actin-related protein 5 {ECO:0000256|ARBA:ARBA00021612};
GN Name=ACTR5 {ECO:0000313|Ensembl:ENSLAFP00000005791.3};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000005791.3, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000005791.3, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000005791.3,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000005791.3}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000005791.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the actin family. ARP5 subfamily.
CC {ECO:0000256|ARBA:ARBA00006021}.
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DR AlphaFoldDB; G3SZ24; -.
DR STRING; 9785.ENSLAFP00000005791; -.
DR Ensembl; ENSLAFT00000006895.3; ENSLAFP00000005791.3; ENSLAFG00000006895.3.
DR eggNOG; KOG0681; Eukaryota.
DR GeneTree; ENSGT00720000108866; -.
DR InParanoid; G3SZ24; -.
DR OMA; CYVSQDY; -.
DR TreeFam; TF324227; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0031011; C:Ino80 complex; IEA:Ensembl.
DR GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR GO; GO:0006302; P:double-strand break repair; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR GO; GO:0033044; P:regulation of chromosome organization; IEA:Ensembl.
DR GO; GO:0006275; P:regulation of DNA replication; IEA:Ensembl.
DR GO; GO:0060382; P:regulation of DNA strand elongation; IEA:Ensembl.
DR GO; GO:0070914; P:UV-damage excision repair; IEA:Ensembl.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 4.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR004001; Actin_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; ACTIN; 1.
DR PANTHER; PTHR11937:SF16; ACTIN-RELATED PROTEIN 5; 1.
DR Pfam; PF00022; Actin; 2.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00432; ACTINS_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT REGION 583..606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 290..324
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 606 AA; 68272 MW; 5B4DB018EA2F085D CRC64;
AANVFPFRDA RSAPDPVLEA GPLAYGPLPV PLVLDNGSFQ ARAGWACPGP DPGPEPRLQF
RAVCARGRGA ARGGPGPQVG NALGSLEPLR WMLRSPFDRN VPVNLELQEL LFDYSFQHLG
VSSQGCVDHP VVLTEAVCNP LYSRQMMSEL LFECYGIPKV AYGIDSLFSF YHNKPKNLTS
SALIISSGYQ CTHILPILEG RLDAKNCKRI NLGGSQAAGY LQRLLQLKYP GHLAAITLSR
MEEILHEHSY VAEDYGEELQ KWRCPDYYEN NVHKMQLPFS SKLLGSTLTS EEKQERRQQQ
LRRLQELNAR RREEKLQLDQ ERLDRLLCVQ ELLEDGQMDQ FHKALIELNM DSPEELQSYI
QKLSSAVEQA KQKILQAEVT LEVDVVDSKP ETPDLEQLEP SLEDVESMND FEPLFSEETP
EVEKPVTTVQ PVFNLAAYHQ LFVGTERIRA PEIIFQPSLI GEEQAGIAET LQYVLDRYPK
DVQETLVQNV FLTGGNMMYP GMKARIEKEL LEMRPFQSCF QVQLAFNPVL DAWYGARDWA
LDHLDNHEVW VTRKEYEEKG GEYLKEHCAS NIYVPIHLPK QASRSSDTQA SGRSTGASGS
SAGEHA
//
