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Database: UniProt
Entry: G3T2P8_LOXAF
LinkDB: G3T2P8_LOXAF
Original site: G3T2P8_LOXAF 
ID   G3T2P8_LOXAF            Unreviewed;      1143 AA.
AC   G3T2P8;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   31-JUL-2019, entry version 50.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLAFP00000007452};
GN   Name=PRDM15 {ECO:0000313|Ensembl:ENSLAFP00000007452};
OS   Loxodonta africana (African elephant).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX   NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000007452, ECO:0000313|Proteomes:UP000007646};
RN   [1] {ECO:0000313|Ensembl:ENSLAFP00000007452}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000007452};
RA   Di Palma F., Heiman D., Young S., Johnson J., Lander E.S.,
RA   Lindblad-Toh K.;
RT   "The Genome Sequence of Loxodonta africana (African elephant).";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLAFP00000007452}
RP   IDENTIFICATION.
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000007452};
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
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DR   STRING; 9785.ENSLAFP00000007452; -.
DR   Ensembl; ENSLAFT00000008873; ENSLAFP00000007452; ENSLAFG00000008866.
DR   eggNOG; KOG1721; Eukaryota.
DR   eggNOG; COG5048; LUCA.
DR   GeneTree; ENSGT00940000157890; -.
DR   InParanoid; G3T2P8; -.
DR   OMA; HKHQNLT; -.
DR   TreeFam; TF331419; -.
DR   Proteomes; UP000007646; Unassembled WGS sequence.
DR   GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR   GO; GO:1990841; F:promoter-specific chromatin binding; IEA:Ensembl.
DR   GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:2000035; P:regulation of stem cell division; IEA:Ensembl.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 5.
DR   SMART; SM00355; ZnF_C2H2; 16.
DR   SUPFAM; SSF57667; SSF57667; 7.
DR   PROSITE; PS50280; SET; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 15.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 14.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007646};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   DOMAIN       49    159       SET. {ECO:0000259|PROSITE:PS50280}.
FT   DOMAIN      197    224       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      370    392       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      402    430       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      463    490       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      490    512       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      539    566       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      566    593       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      657    684       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      693    720       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      721    748       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      749    776       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      777    804       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      805    832       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      833    861       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   REGION      222    278       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      607    626       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      926    975       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1113   1143       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS   1126   1143       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   1143 AA;  129883 MW;  D10AE80CEABC5BB2 CRC64;
     MAEDGSEEIM FIWCEDCSQY HDSECPELGP VVMVKDSFVL SRARSSLPSN LEIRRLEDGT
     EGVFAVTQLV KRTQFGPFES RRVAKWEKES AFPLKVFQKD GHPVCFDTSN EDDCNWMMLV
     RPAVEHEHQN LTAYQQDSDV YFTTSRDIPP GTELRVWYAA FYAKKMDKPM LKQACAGAHA
     AGTPESSALV EAEPSQWACK VCSATFLELQ LLNEHLLTHL EQAKGAPPPS QSEATPEKEP
     EAPQGEPPTG PQTVSATKEL KKKPRRGRKP KAPRTEQPLV IVEDKDPAEH VAEIVTEVPP
     DEPVSAAPDE RIMELVLGKL ATATSDSGSV PKFTHPPHST ISLKRSLILS SRHGIRRKLI
     RQLGEHKRVY QCNTCSKVFQ NSSNLSRHVR SHGECPISDK LFKCEECAKL FSRKESLKQH
     VSYKHSRNEV DSEYRYRCGT CEKAFRIESA LEFHNCRTDD KTFQCEMCFR FFSTNSNLSK
     HKKKHGDKKF ACEVCNKMFY RKDVMLDHQR RHLEGVRRVK REDLEASSEN LVRYKKEPSG
     CPVCGKVFSC RSNMNKHLLT HGDKKYTCEI CGRKFFRVDV LRDHIHVHFK DIALMDDHQR
     EEFIGKIGIS SEENDDNSDE SADSEPHKYS CKRCQLTFGR GKEYLKHIME VHKEKGYGCS
     ICHRRFALKA TYHAHMVIHR ENLPDPNVQK YIHPCEICGR IFNSIGNLER HKLIHTGVKS
     HACEQCGKSF ARKDMLKEHM RVHDNIREYL CAECGKGMKT KHALRHHMKL HKGIKEYECK
     ECHRKFAQKV NMLKHYKRHT GIKDFMCELC GKTFSERNTM ETHKLIHTVG KQWTCSVCDK
     KYVTEYMLQK HVQLTHDKVE AQSCQLCGTK VSTRASMSRH MRRKHPEVLA VRIDDLDHLP
     ETTTIDASSI GIVQPELTLE QEELAEGKHV KAAKRTHKRK QKPEESGAPV PESATFSEYP
     EKETEFAGSS VGDETNSAVQ SIQQVVVTLG DPNVTTPSSS VGLTNITVTP ITTAAGTQFT
     NLQPVAVGHL TTPERQLQLD NSILTVTFDT VSGSAMLHNR QNDIQIHPQP EASNPQSVAH
     FINLTTLVNS ITPLGNQLSE QHPLAWRAVP QTDVLQPPQP QPPQQQAAQP QVQTEPQQQM
     YSY
//
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