ID G3TAL7_LOXAF Unreviewed; 1177 AA.
AC G3TAL7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Atrophin 1 {ECO:0000313|Ensembl:ENSLAFP00000010928.3};
GN Name=ATN1 {ECO:0000313|Ensembl:ENSLAFP00000010928.3};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000010928.3, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000010928.3, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000010928.3,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000010928.3}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000010928.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; G3TAL7; -.
DR STRING; 9785.ENSLAFP00000010928; -.
DR Ensembl; ENSLAFT00000013064.3; ENSLAFP00000010928.3; ENSLAFG00000013065.3.
DR eggNOG; KOG2133; Eukaryota.
DR GeneTree; ENSGT00940000153615; -.
DR HOGENOM; CLU_005292_0_0_1; -.
DR InParanoid; G3TAL7; -.
DR OMA; YPHSLES; -.
DR TreeFam; TF328554; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0019904; F:protein domain specific binding; IEA:Ensembl.
DR GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR GO; GO:0001906; P:cell killing; IEA:Ensembl.
DR GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR GO; GO:0008340; P:determination of adult lifespan; IEA:Ensembl.
DR GO; GO:0030011; P:maintenance of cell polarity; IEA:Ensembl.
DR GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR GO; GO:0032094; P:response to food; IEA:Ensembl.
DR GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR InterPro; IPR017993; Atrophin-1.
DR InterPro; IPR002951; Atrophin-like.
DR PANTHER; PTHR13859:SF9; ATROPHIN-1; 1.
DR PANTHER; PTHR13859; ATROPHIN-RELATED; 1.
DR Pfam; PF03154; Atrophin-1; 2.
DR PRINTS; PR01222; ATROPHIN.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REGION 1..597
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 609..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 775..849
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 915..934
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..95
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..127
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..174
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..220
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..312
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..369
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..581
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 670..705
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..741
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..830
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1177 AA; 123543 MW; 902FD60FA2A2FB98 CRC64;
MKTRQNKDSM SMRSGRKKEA PGPREELRSR GRASPGGVST SSSDGKAEKS RQTAKKARVE
EASTPKVSKQ GRSEEISESE SEETSAPKKT KTEQELPRPQ SPSDLDSLDG RSLNDDGSSD
PRDIDQDNRS TSPSIYSPGS VENDSDSSSG LSQGPARPYH PPPLFPPSSP PADSTPRQAE
PGFESHPSVT PTGYHAAMDP PTSRMFQAPP GAPPPHPQLY PAGAGGGVLS GPPMGPKGGG
AASSVGVPSG GKQHPPPTTP ISISSSGAGG VPPTKAPTTP VGGGNLPSAP PPATFPHVTP
NLPPPPALRP LNNASASPPG LGAQPLPGHL PSPHAMGQGM GGLPPGPEKG PTLAPSPHPL
PPASSSSAPA PPMRYPYSSS NSSAVASSSS SSSSSSASQY PASQALPSYP HSFPPPTSLS
VSNQPPKYTQ PSLPSQAVWS QGPPPPPPYG RLLANSNAHS GPFPPSTGGQ STAHPSAPTH
HHHQQQQQQQ HHGSSGPPAP GAYPHPLEGS SSHHAHPYAM SPSLGSLRPY PPGPAHLPPP
HSQVSYSQAG PNGPPASSSS SNSSSSQGSY PCSHPSPSQG SQGAPYPFPP VPPVTTSSAT
LSTVIATVAS SPASYKTASP PGPPPYGKRA PSPGAYKTAT PPGYKPGSPP SFRTGTPPGY
RGTSPPVGPG TFKPGSPTVG PGPIPSAGPS GLSSLPPPPS APASGPPLSA TQIKQEPAEE
YEPPESPVPP ARSPSPPPKV VDVPSHASQS ARFNKHLDRG FNSCARSDLY FVPLEGSKLA
KKRADLVEKV RREAEQRARE EKERERERER EKEREREKER ELERSVKLAQ EGRAPVECPS
LGPVPHRPPF EPGSAVATVP PYLGPDTPAL RTLSEYARPH VMSPGNRNHP FYVPLGAVDP
GLLGYNVPAL YSSDPAARER EREARERDLR DRLKPGFEVK PSELEPLHGV PGPGLDPFPR
HGGLALQPGP PGLHPFPFHP SLGPLERERL ALAAGPALRP DMSYAERLAA ERQHAERVAA
LGNDPLARLQ MLNVTPHHHQ HSHIHSHLHL HQQDAIHAAS ASVHPLIDPL ASGSHLTRIP
YPAGTLPNPL LPHPLHENEV LRHQLFAAPY RDLPASLSAP MSAAHQLQAM HAQSAELQRL
ALEQQQWLHA HHPLHSVPLP AQEDYYSHLK KESDKPL
//
