ID   G3TAS7_LOXAF            Unreviewed;       309 AA.
AC   G3TAS7;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Interleukin 13 receptor subunit alpha 2 {ECO:0000313|Ensembl:ENSLAFP00000011005.3};
GN   Name=IL13RA2 {ECO:0000313|Ensembl:ENSLAFP00000011005.3};
OS   Loxodonta africana (African elephant).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX   NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000011005.3, ECO:0000313|Proteomes:UP000007646};
RN   [1] {ECO:0000313|Ensembl:ENSLAFP00000011005.3, ECO:0000313|Proteomes:UP000007646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000011005.3,
RC   ECO:0000313|Proteomes:UP000007646};
RA   Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Loxodonta africana (African elephant).";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLAFP00000011005.3}
RP   IDENTIFICATION.
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000011005.3};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; G3TAS7; -.
DR   Ensembl; ENSLAFT00000013152.3; ENSLAFP00000011005.3; ENSLAFG00000013156.3.
DR   GeneTree; ENSGT00940000159971; -.
DR   HOGENOM; CLU_054773_1_0_1; -.
DR   Proteomes; UP000007646; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003532; Short_hematopoietin_rcpt_2_CS.
DR   InterPro; IPR015321; TypeI_recpt_CBD.
DR   PANTHER; PTHR23036; CYTOKINE RECEPTOR; 1.
DR   PANTHER; PTHR23036:SF101; INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-2; 1.
DR   Pfam; PF09240; IL6Ra-bind; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 3.
DR   PROSITE; PS01356; HEMATOPO_REC_S_F2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT   DOMAIN          118..211
FT                   /note="Type I cytokine receptor cytokine-binding"
FT                   /evidence="ECO:0000259|Pfam:PF09240"
SQ   SEQUENCE   309 AA;  35925 MW;  09B15FF37FD725FD CRC64;
     HKIQDKTVNP PQDFEIVDPG YLGYLCLQWK PPLFLDNFKE CTVEYELKYR NFGSKIWKTI
     ITTNLYYKDG FDLNKGVEAK IHTLLPQQCT NESTVRSLWS EATYWTPPQG NVETKIQDMD
     CVYYNWLYLF CSWKPGMDVP LDTNYNLFYW YDGLDHPMQC DDYMTINGQN TGCSFPSLKS
     PDYKDFYICV NGSSRSTAIR PSYFIFQLQN IVKPLPPDYV SLTLKDSNEV ILKWSVPAGP
     IPAACFIYEV LVTEDDTTRV STTIENEMCI TRKSNKSNQV CFLVKSKVNI YCSETGIWSE
     WSEEQCWRG
//