ID G3TD10_LOXAF Unreviewed; 362 AA.
AC G3TD10;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Mitochondrial import receptor subunit TOM40 homolog {ECO:0000256|ARBA:ARBA00039690};
DE AltName: Full=Translocase of outer membrane 40 kDa subunit homolog {ECO:0000256|ARBA:ARBA00041730};
GN Name=TOMM40 {ECO:0000313|Ensembl:ENSLAFP00000011996.2};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000011996.2, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000011996.2, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000011996.2,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000011996.2}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000011996.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC outer membrane {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004374}.
CC -!- SIMILARITY: Belongs to the Tom40 family.
CC {ECO:0000256|ARBA:ARBA00010510}.
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DR RefSeq; XP_003406534.1; XM_003406486.2.
DR AlphaFoldDB; G3TD10; -.
DR STRING; 9785.ENSLAFP00000011996; -.
DR Ensembl; ENSLAFT00000014324.2; ENSLAFP00000011996.2; ENSLAFG00000014323.2.
DR GeneID; 100661038; -.
DR KEGG; lav:100661038; -.
DR CTD; 10452; -.
DR eggNOG; KOG3296; Eukaryota.
DR GeneTree; ENSGT00390000003308; -.
DR InParanoid; G3TD10; -.
DR OMA; TRFNYRW; -.
DR OrthoDB; 5489886at2759; -.
DR TreeFam; TF106204; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0044233; C:mitochondria-associated endoplasmic reticulum membrane; IEA:Ensembl.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:Ensembl.
DR GO; GO:0005742; C:mitochondrial outer membrane translocase complex; IEA:Ensembl.
DR GO; GO:0008320; F:protein transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0030150; P:protein import into mitochondrial matrix; IEA:InterPro.
DR CDD; cd07305; Porin3_Tom40; 1.
DR Gene3D; 2.40.160.10; Porin; 1.
DR InterPro; IPR023614; Porin_dom_sf.
DR InterPro; IPR027246; Porin_Euk/Tom40.
DR InterPro; IPR037930; Tom40.
DR PANTHER; PTHR10802; MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40; 1.
DR PANTHER; PTHR10802:SF1; MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 HOMOLOG; 1.
DR Pfam; PF01459; Porin_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00022787};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT REGION 1..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..37
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 362 AA; 37730 MW; 9433FD8DE088F0DD CRC64;
MGNVLAASSP PAGPPPPPAP ALVGLPPPPP APPGFTLPPL GGGLGAGAAA GRGSERTPGA
PAAASAAGTA DDGAGGCLPN PGTFEECHRK CKELFPIQME GVKLIVNKGL SNHFQVNHTV
ALSTVGESNY HFGVTYVGTK QLSPTEAFPV LVGDMDNSGS LNAQVIHQLG PGLRSKMAIQ
TQQSKFVNWQ VDGEYRGSDF TAAVTLGNPD VLVGSGILVA HYLQSITPCL ALGGELVYHR
RPGEEGTVMS LAGKYTLNNW LATVTLGQAG MHATYYHKAS DQLQVGVEFE ASTRMQDTSV
SFGYQLDLPK ANLLFKGSVD SNWIVGATLE KKLPPLPLTL ALGAFLNHRK NKFQCGFGLT
IG
//
