ID G3TFZ8_LOXAF Unreviewed; 543 AA.
AC G3TFZ8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=SRY-box transcription factor 13 {ECO:0000313|Ensembl:ENSLAFP00000013355.3};
GN Name=SOX13 {ECO:0000313|Ensembl:ENSLAFP00000013355.3};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000013355.3, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000013355.3, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000013355.3,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000013355.3}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000013355.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3TFZ8; -.
DR Ensembl; ENSLAFT00000015927.3; ENSLAFP00000013355.3; ENSLAFG00000015918.3.
DR GeneTree; ENSGT00940000158759; -.
DR HOGENOM; CLU_018522_1_1_1; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22030; HMG-box_SoxD; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR45789; FI18025P1; 1.
DR PANTHER; PTHR45789:SF4; TRANSCRIPTION FACTOR SOX-13; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT DOMAIN 351..419
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 351..419
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 154..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..543
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 100..137
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 221..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..527
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 528..543
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 543 AA; 60462 MW; D0D6DA7D84DAC0F5 CRC64;
GSPEPKRPGT AEAASVSQEK LDFNRNLKEV VPAIEKLLSS DWKERFLGRS SVETKDVKGT
QESLAEKELQ LLVMIPPIVY SSDQLLTAHS EQKNMAAMLF EKQQQQMELA RQQQEQIAKQ
QQQLIQQQHK INLLQQQIQQ VNMPYVMIPA FPPTHQPLPV TPDSQLALPR GHGERQGPQD
FSPCRLFHSG VSAAAAAQPP CPSGSPQEPS QPLNLTAKPK APEPPSTSSS PSLKMSNCGP
RPPSHGASLS LPSPPFPTGF LGEGDAVTKA IQDARQLLHG HSAALESSPN TPFRKDLISL
DSSPAKERLE ESCVHPLEEA MLSCDMDGEG PGLGADGRSR HFPESRNSSH IKRPMNAFMV
WAKDERRKIL QAFPDMHNSS ISKILGSRWK AMTNQEKQPY YEEQARLSRQ HLEKYPDYKY
KPRPKRTCIV EGKRLRVGEY KALMRTRRQD ARQSYVIPPQ AGQVQLSSTD VLYPRAAGMP
LAQPLVEHYV PRSLDPNMPV IVNTCSLREE GEGAEDRHSA ADGEMYRYSE DDDSEGEEKS
DGE
//
