ID G3TGT6_LOXAF Unreviewed; 624 AA.
AC G3TGT6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Cap binding complex dependent translation initiation factor {ECO:0000313|Ensembl:ENSLAFP00000013715.3};
GN Name=CTIF {ECO:0000313|Ensembl:ENSLAFP00000013715.3};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000013715.3, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000013715.3, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000013715.3,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000013715.3}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000013715.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3TGT6; -.
DR STRING; 9785.ENSLAFP00000013715; -.
DR Ensembl; ENSLAFT00000016333.3; ENSLAFP00000013715.3; ENSLAFG00000016335.3.
DR eggNOG; KOG3942; Eukaryota.
DR GeneTree; ENSGT00940000153432; -.
DR HOGENOM; CLU_031968_1_0_1; -.
DR InParanoid; G3TGT6; -.
DR OMA; ELHAHCW; -.
DR TreeFam; TF350740; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:Ensembl.
DR GO; GO:0006446; P:regulation of translational initiation; IEA:Ensembl.
DR Gene3D; 1.25.40.180; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR23254:SF16; CBP80_20-DEPENDENT TRANSLATION INITIATION FACTOR; 1.
DR PANTHER; PTHR23254; EIF4G DOMAIN PROTEIN; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT DOMAIN 402..603
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..280
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..335
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 624 AA; 70037 MW; 83E541686A4739B7 CRC64;
MENSSAASAS SEAGSNRSQE IEELERFIDS YVLEYQVQGL LSDKTEGDGE SEKTQSHISQ
WTADCSERLN SSCSFSRGRA PPQQVGNREN PMDHTGAGVW GAWSFPLFPH ACYIHLTCSH
CSATCQHLSC PASLAPPAPS WPGEKCGKGK LEDGEGINLN DIEKVLPAWQ GYHPMPHEAE
IAHTKKLFRR RRNDRRRQQR PPGGNKPQQH GDHQPGSAKH NRDHQKSYQG GSAPHPSGRP
THHGYSQNRR WHHSNMKHPP GDKGEAGAHR NAKETVTFEG SKLEDAPGDT GHGALETPRS
PEALALVAPE RLPPQQPGGP EAETKRKDSV IPERIGERPK ITLLQSSKDR LRRRLKEKVR
ALPRSAESLR DMRAWLGLSP TPQDEVTVET TSPQQNKMDK LIEILNSMRN NSSDVDAKLT
TFMEEAQNST NSEEMLGEIV RTIYQKAVSD RSFAFTAAKL CDKMALFMVE GTKFRSLLLN
MLQKDFTVRE ELQQQDVERW LGFITFLCEV FGTMRSSTGE PFRVLVCPIY TCLRELLQSQ
DVKEDAVLCC SMELQSTGRL LEEQLPEMMM ELLASARDKM LCPSESMLTR SLLLEVIELH
ANSWNPLTPP ITQYYNRTIQ KLTA
//
