ID G3THK3_LOXAF Unreviewed; 739 AA.
AC G3THK3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Heterogeneous nuclear ribonucleoprotein U like 1 {ECO:0000313|Ensembl:ENSLAFP00000014058.3};
GN Name=HNRNPUL1 {ECO:0000313|Ensembl:ENSLAFP00000014058.3};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000014058.3, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000014058.3, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000014058.3,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000014058.3}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000014058.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; G3THK3; -.
DR STRING; 9785.ENSLAFP00000014058; -.
DR Ensembl; ENSLAFT00000016758.3; ENSLAFP00000014058.3; ENSLAFG00000016754.3.
DR eggNOG; KOG2242; Eukaryota.
DR GeneTree; ENSGT00940000157823; -.
DR HOGENOM; CLU_012140_0_1_1; -.
DR InParanoid; G3THK3; -.
DR OMA; FFEMAPR; -.
DR TreeFam; TF317301; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0045202; C:synapse; IEA:Ensembl.
DR GO; GO:0019899; F:enzyme binding; IEA:Ensembl.
DR CDD; cd12884; SPRY_hnRNP; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR035778; SPRY_hnRNP_U.
DR PANTHER; PTHR12381; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER; 1.
DR PANTHER; PTHR12381:SF41; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 1; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT DOMAIN 95..292
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 1..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 499..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..103
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..518
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 655..669
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..692
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 739 AA; 83109 MW; BF1515F4066B630C CRC64;
MDNITRQNQF YESQVIKQEN ESGYERRPLE MEPQQQAYRP VEMKTEMKPE VPTSFFPHEA
SQPKPDRQQF QSRKRPYEEN RGRGYFEHRE DRRHRGRSPQ PPAEEDEDDF DDTLVAIDTY
NCDLHFKVAR DRSSGYPLTI EGFAYLWSGA RASYGVRRGR VCFEMKINEE ISVKHLPSTE
PDPHVVRIGW SLDSCSTQLG EEPFSYGYGG TGKKSTNSRF ENYGDKFAEN DVIGCFADFE
CGNDVELSFT KNGKWMGIAF RIQKEALGGQ ALYPHVLVKN CAVEFNFGQR AEPYCSVLPG
FTFIQHLPLG ERIRGTVGPK SKADCEILMM VGLPAAGKTT WAIKHAASNP SKKYNILGTN
AIMDKMRVMG LRRQRNYAGR WDVLIQQATQ CLNRLIQIAA RKKRNYILDQ TNVYGSAQRR
KMRPFEGFQR KAIVICPTDE DLKDRTIKRT DEEGKDVPDH AVLEMKANFT LPDVGDFLDE
VLFIELQREE ADKLVRQYNE EGRKAGPPPE KRFDNRGGGG FRGRGGGGGF QRYDNRAPPG
GNRGGFQNRG GGGGGGGNYR GGFNRSGGGG YNQNRWGNNN RDNNNSNNRG SYNRTPQQPS
YSPARNPPGA SSYNKNSSIP GSSVNTSTPT VSSYSPPQPS YSQPPYNQGG YTQAYTAPPP
PPPPPPAYNY GTYGGYNPAP YTPPPPPAAQ TYPQPSYNQY QQYAQQWNQY YQNGQWPPYY
GNYDYGSYSG STQGGTSTQ
//
