ID G3THX4_LOXAF Unreviewed; 160 AA.
AC G3THX4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Growth arrest and DNA damage inducible beta {ECO:0000313|Ensembl:ENSLAFP00000014208.1};
GN Name=GADD45B {ECO:0000313|Ensembl:ENSLAFP00000014208.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000014208.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000014208.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000014208.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000014208.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000014208.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GADD45 family.
CC {ECO:0000256|ARBA:ARBA00007361}.
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DR RefSeq; XP_003422152.1; XM_003422104.2.
DR AlphaFoldDB; G3THX4; -.
DR STRING; 9785.ENSLAFP00000014208; -.
DR Ensembl; ENSLAFT00000016946.1; ENSLAFP00000014208.1; ENSLAFG00000016948.1.
DR GeneID; 100655692; -.
DR KEGG; lav:100655692; -.
DR CTD; 4616; -.
DR eggNOG; ENOG502RY00; Eukaryota.
DR GeneTree; ENSGT00950000182964; -.
DR HOGENOM; CLU_118164_0_0_1; -.
DR InParanoid; G3THX4; -.
DR OMA; YCEESRE; -.
DR OrthoDB; 4103218at2759; -.
DR TreeFam; TF300196; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR GO; GO:0046330; P:positive regulation of JNK cascade; IEA:Ensembl.
DR GO; GO:1900745; P:positive regulation of p38MAPK cascade; IEA:Ensembl.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR Gene3D; 3.30.1330.30; -; 1.
DR InterPro; IPR024824; GADD45.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004038; Ribosomal_eL8/eL30/eS12/Gad45.
DR PANTHER; PTHR10411; GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45; 1.
DR PANTHER; PTHR10411:SF5; GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 BETA; 1.
DR Pfam; PF01248; Ribosomal_L7Ae; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT DOMAIN 22..119
FT /note="Ribosomal protein eL8/eL30/eS12/Gadd45"
FT /evidence="ECO:0000259|Pfam:PF01248"
SQ SEQUENCE 160 AA; 17815 MW; 4FD291AFB5611068 CRC64;
MTLEEIVACD NAAQKMQTVS AAVEELLVAA QCQDRLTVGV YESAKLMNVD PDSVVLCLLA
IDEEEEDDIA LQIHFTLIQS FCCDNDIDIV RVSGMQRLAQ LLGEPAETQG TTEPRDLHCL
LVTNPHTDAW KSHGLVEVAN YCEESRGNNQ WVPYIPLQER
//
