ID G3TJW7_LOXAF Unreviewed; 206 AA.
AC G3TJW7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=CD83 molecule {ECO:0000313|Ensembl:ENSLAFP00000015061.3};
GN Name=CD83 {ECO:0000313|Ensembl:ENSLAFP00000015061.3};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000015061.3, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000015061.3, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000015061.3,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000015061.3}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000015061.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3TJW7; -.
DR STRING; 9785.ENSLAFP00000015061; -.
DR Ensembl; ENSLAFT00000017966.3; ENSLAFP00000015061.3; ENSLAFG00000017967.3.
DR eggNOG; ENOG502S7FP; Eukaryota.
DR GeneTree; ENSGT00390000007302; -.
DR HOGENOM; CLU_099481_0_0_1; -.
DR InParanoid; G3TJW7; -.
DR OMA; SKPGMER; -.
DR TreeFam; TF337861; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
DR GO; GO:0043367; P:CD4-positive, alpha-beta T cell differentiation; IEA:Ensembl.
DR GO; GO:0032713; P:negative regulation of interleukin-4 production; IEA:Ensembl.
DR GO; GO:0043372; P:positive regulation of CD4-positive, alpha-beta T cell differentiation; IEA:Ensembl.
DR GO; GO:0032733; P:positive regulation of interleukin-10 production; IEA:Ensembl.
DR GO; GO:0032743; P:positive regulation of interleukin-2 production; IEA:Ensembl.
DR GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR15193; CD83 ANTIGEN; 1.
DR PANTHER; PTHR15193:SF1; CD83 ANTIGEN; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..206
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003455573"
FT TRANSMEM 146..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..124
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 206 AA; 23398 MW; E3D174F5C18FEEF9 CRC64;
MTRGLQFLLL SCACGVTLAA RDIKVVCSED VDLPCTAPWD PQVSYTVSWT KLTEVGEELM
EVRQEDLSTR EQYYYQKERN SSLEAPSEGL YSLKIRNTTS CDTGTYRCML WDLEGQRNQS
GTVTLRVIDA QCNAKEENFK KYRAEIVLLL ALVVFYLTLI IFTCKFAKLQ SIFPDVAKPG
MERAFFPVTS QNKHLGPVIV QKTELV
//
