ID G3TMF7_LOXAF Unreviewed; 743 AA.
AC G3TMF7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=F-box protein 30 {ECO:0000313|Ensembl:ENSLAFP00000016292.2};
GN Name=FBXO30 {ECO:0000313|Ensembl:ENSLAFP00000016292.2};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000016292.2, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000016292.2, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000016292.2,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000016292.2}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000016292.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_010585771.1; XM_010587469.1.
DR RefSeq; XP_010585807.1; XM_010587505.1.
DR AlphaFoldDB; G3TMF7; -.
DR STRING; 9785.ENSLAFP00000016292; -.
DR Ensembl; ENSLAFT00000008595.3; ENSLAFP00000016292.2; ENSLAFG00000008596.3.
DR GeneID; 100655503; -.
DR KEGG; lav:100655503; -.
DR CTD; 84085; -.
DR eggNOG; ENOG502QTD9; Eukaryota.
DR GeneTree; ENSGT00950000183204; -.
DR HOGENOM; CLU_013357_0_0_1; -.
DR InParanoid; G3TMF7; -.
DR OMA; HILMPDG; -.
DR OrthoDB; 5397239at2759; -.
DR TreeFam; TF343227; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd22174; F-box_FBXO30; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 3.30.40.150; TRAF-like zinc-finger, N-terminal subdomain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR031890; Fbxo30/Fbxo40.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001293; Znf_TRAF.
DR InterPro; IPR043013; Znf_TRAF_N.
DR PANTHER; PTHR15933:SF13; F-BOX ONLY PROTEIN 30; 1.
DR PANTHER; PTHR15933; PROTEIN CBG16327; 1.
DR Pfam; PF15966; F-box_4; 1.
DR Pfam; PF15965; zf-TRAF_2; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS50145; ZF_TRAF; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207}; Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 49..91
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 608..644
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT ZN_FING 49..91
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
SQ SEQUENCE 743 AA; 82402 MW; 274EB2FF9ECDE7D1 CRC64;
MEEELQHSHC VNCVSRRCMT RPEPGISCDL IGCPLVCGAV FHSCKADEHR LLCPFERVPC
LNSDFGCPFT MARNKVAEHL ETCPASVVCC TMEWNRWPVS YADRKSYEIL SKDVDEVAQL
DMALALQDQR MLLESLKVAT MMSKATEKVS EAREQISVKS SVPEIPHTNG LVSVDEKSYG
ALYQATVETT RSLAAALDIL NTATRDIGML STSLCVSPDE IDEEQNTRES LQDRNLKDQD
LLYEDEIGAV GGIDHHDTIQ NAQPEQNGSS DLLCDLDTSS HGTSLCNGFP LGNICTQVQN
QNLHGDSKQT NLTNGECVAS DDTSKPSSSL SIAAQLREVI PPSPLPNGTV QHILMPGDED
EGELYCRKVD LGDLKNMDVL PFGMPSFKYF SNSCWCKSME DKAVDTSDLE VAEDPMGLQG
IDLITAALLF CLGDSPGGRG ISDSRMVDVY HIDFGTQTFS LPSAILATNT MVGEIASASA
CDHANPQLSN PSPFQTLGLD LVLECVARYQ PKQRSMFTFV CGQLFRRKEF SSHFKNVHGD
IHAGLNGWME QRCPLAYYGC TYSQRRFCPS TQGAKIIHDR HLRSFGIQPC ISTVLVEPAR
NCVLGLHSDH LSSLPFEVLQ HIAGFLDGFS LCQLSRVSRL MRDVCGSLLQ SRGMVILQWG
KRKYPDGNSS WQIKEKVWRF STAFCSVNEW KFADILSMAD HLKRCSYNIV EKREEAIPLP
CMCVTRELTR EGRSLRSVLK PVL
//
