ID   G3TQV2_LOXAF            Unreviewed;       353 AA.
AC   G3TQV2;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   RecName: Full=Kelch domain-containing protein 8B {ECO:0000256|ARBA:ARBA00041086};
GN   Name=KLHDC8B {ECO:0000313|Ensembl:ENSLAFP00000017960.1};
OS   Loxodonta africana (African elephant).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX   NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000017960.1, ECO:0000313|Proteomes:UP000007646};
RN   [1] {ECO:0000313|Ensembl:ENSLAFP00000017960.1, ECO:0000313|Proteomes:UP000007646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000017960.1,
RC   ECO:0000313|Proteomes:UP000007646};
RA   Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Loxodonta africana (African elephant).";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLAFP00000017960.1}
RP   IDENTIFICATION.
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000017960.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Midbody {ECO:0000256|ARBA:ARBA00004214}.
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DR   AlphaFoldDB; G3TQV2; -.
DR   STRING; 9785.ENSLAFP00000017960; -.
DR   Ensembl; ENSLAFT00000033307.1; ENSLAFP00000017960.1; ENSLAFG00000005090.2.
DR   eggNOG; KOG1072; Eukaryota.
DR   GeneTree; ENSGT00940000160815; -.
DR   InParanoid; G3TQV2; -.
DR   OMA; VWIKPSR; -.
DR   Proteomes; UP000007646; Unassembled WGS sequence.
DR   GO; GO:0110070; C:cellularization cleavage furrow; IEA:Ensembl.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0045171; C:intercellular bridge; IEA:Ensembl.
DR   GO; GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
DR   GO; GO:1902410; P:mitotic cytokinetic process; IEA:Ensembl.
DR   GO; GO:0140014; P:mitotic nuclear division; IEA:Ensembl.
DR   GO; GO:0098813; P:nuclear chromosome segregation; IEA:Ensembl.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   PANTHER; PTHR46260:SF2; KELCH DOMAIN-CONTAINING PROTEIN 8B; 1.
DR   PANTHER; PTHR46260; RING-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01344; Kelch_1; 5.
DR   SMART; SM00612; Kelch; 5.
DR   SUPFAM; SSF117281; Kelch motif; 2.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ   SEQUENCE   353 AA;  37528 MW;  361FAAC6240FDC11 CRC64;
     MATSGGRAFV WQVFPPMPTC RVYGTVAHQD GHLLVLGGCG QAGLPLDTTE ALDMASHTWL
     ALAPLPTARA GAAAVVLGKQ VLVVGGVDEG QSPVAAVEAF LADEGRWERR ATLPQAAMGS
     FDCGESADGM VYALGGMGPD TAPQAQVRVY EPRQDCWLSL PSMPTPCYGA STFLHGNKIY
     VLGGRQGKLP VTAFEAFDLE ARTWTRHPSL PSRRAFAGCA MAEGSVFSLG GLQQPGPHNF
     YSRPHFVNTV EMFDLEHGSW TKLPRNLRMR DKRADFVVGS LGSHIVAIGG LGNQPCPLGS
     VEGFSLARRR WEALPTMPTA RCSCSSLQTG PHLFVIGGVA QGPSQAVEAL CLR
//