ID G3TSN2_LOXAF Unreviewed; 243 AA.
AC G3TSN2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=IZUMO1 receptor, JUNO {ECO:0000313|Ensembl:ENSLAFP00000018590.1};
GN Name=IZUMO1R {ECO:0000313|Ensembl:ENSLAFP00000018590.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000018590.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000018590.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000018590.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000018590.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000018590.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the folate receptor family.
CC {ECO:0000256|ARBA:ARBA00007932}.
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DR RefSeq; XP_010593777.1; XM_010595475.1.
DR AlphaFoldDB; G3TSN2; -.
DR Ensembl; ENSLAFT00000035118.1; ENSLAFP00000018590.1; ENSLAFG00000032394.1.
DR GeneID; 100672455; -.
DR KEGG; lav:100672455; -.
DR CTD; 390243; -.
DR eggNOG; ENOG502RYYP; Eukaryota.
DR GeneTree; ENSGT00950000183144; -.
DR HOGENOM; CLU_070826_1_0_1; -.
DR InParanoid; G3TSN2; -.
DR OMA; NAPLCQE; -.
DR OrthoDB; 2905009at2759; -.
DR TreeFam; TF328532; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0038023; F:signaling receptor activity; IEA:Ensembl.
DR GO; GO:0005102; F:signaling receptor binding; IEA:Ensembl.
DR GO; GO:0007155; P:cell adhesion; IEA:Ensembl.
DR GO; GO:0007342; P:fusion of sperm to egg plasma membrane involved in single fertilization; IEA:Ensembl.
DR GO; GO:0035036; P:sperm-egg recognition; IEA:Ensembl.
DR InterPro; IPR004269; Folate_rcpt.
DR InterPro; IPR018143; Folate_rcpt-like.
DR PANTHER; PTHR10517; FOLATE RECEPTOR; 1.
DR PANTHER; PTHR10517:SF10; SPERM-EGG FUSION PROTEIN JUNO; 1.
DR Pfam; PF03024; Folate_rec; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..243
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003455749"
FT DOMAIN 26..201
FT /note="Folate receptor-like"
FT /evidence="ECO:0000259|Pfam:PF03024"
SQ SEQUENCE 243 AA; 28159 MW; 4FFE93B3DE2BFF35 CRC64;
MAWWWRLLLG MWTVTTTWSQ DKLLNVCMNT KHHKTEPSPE DKLYEECTPW KDNACCTANT
SWEAHLDMSL LYNFSLTHCG LLTPSCQKHF IQAFCFYECS PNLGPWIQQV DPRGQEEGIV
GVPLCWEDCE QWWDDCRSSY TCKSNWQGGW DWRRGKVRCP AGAHCLPFPD YFPTPADLCD
KIWSNSYKAS PERRSSGRCM QKWFEPAQGN PNVAVARLFA NPARSWELSC PLLVLSLFLS
FHS
//
