ID G3TT77_LOXAF Unreviewed; 342 AA.
AC G3TT77;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Pre-mRNA-splicing factor 18 {ECO:0000256|ARBA:ARBA00018242};
DE AltName: Full=PRP18 homolog {ECO:0000256|ARBA:ARBA00031388};
GN Name=PRPF18 {ECO:0000313|Ensembl:ENSLAFP00000018785.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000018785.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000018785.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000018785.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000018785.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000018785.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PRP18 family.
CC {ECO:0000256|ARBA:ARBA00008137}.
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DR RefSeq; XP_003410625.1; XM_003410577.2.
DR AlphaFoldDB; G3TT77; -.
DR SMR; G3TT77; -.
DR Ensembl; ENSLAFT00000033378.1; ENSLAFP00000018785.1; ENSLAFG00000007753.3.
DR GeneID; 100675941; -.
DR KEGG; lav:100675941; -.
DR CTD; 8559; -.
DR GeneTree; ENSGT00390000015073; -.
DR HOGENOM; CLU_039675_0_1_1; -.
DR OrthoDB; 199348at2759; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR Gene3D; 1.20.940.10; Functional domain of the splicing factor Prp18; 1.
DR Gene3D; 4.10.280.110; Pre-mRNA processing factor 4 domain; 1.
DR InterPro; IPR004098; Prp18.
DR InterPro; IPR014906; PRP4-like.
DR InterPro; IPR036285; PRP4-like_sf.
DR InterPro; IPR039979; PRPF18.
DR PANTHER; PTHR13007; PRE-MRNA SPLICING FACTOR-RELATED; 1.
DR PANTHER; PTHR13007:SF19; PRE-MRNA-SPLICING FACTOR 18; 1.
DR Pfam; PF02840; Prp18; 1.
DR Pfam; PF08799; PRP4; 1.
DR SMART; SM00500; SFM; 1.
DR SUPFAM; SSF47938; Functional domain of the splicing factor Prp18; 1.
DR SUPFAM; SSF158230; PRP4-like; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 79..129
FT /note="Pre-mRNA processing factor 4 (PRP4)-like"
FT /evidence="ECO:0000259|SMART:SM00500"
SQ SEQUENCE 342 AA; 39860 MW; 269D79E1E733CF6D CRC64;
MDILKSEILR KRQLVEDRNL LVENKKYFKR SELAKKEEEA YFERCGYKIQ PKEEDQKPLT
SSNPVLELEL AEEKLPMTLS RQEVIRRLRE RGEPIRLFGE TDYDAFQRLR KIEILTPEVN
KGLRNDLKAA LDKIDQQYLN EIVGGQEPGE EDTQNDLKVH EENTTIEELE ALGESLGKGD
DHKDMDIITK FLKFLLGVWA KELNAREDYV KRSVQGKLNS ATQKQTESYL RPLFRKLRKR
NLPADIKESI TDIIKFMLQR EYVKANDAYL QMAIGNAPWP IGVTMVGIHA RTGREKIFSK
HVAHVLNDET QRKYIQGLKR LMTICQKHFP TDPSKCVEYN AL
//
