ID   G3TXD5_LOXAF            Unreviewed;       577 AA.
AC   G3TXD5;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=XK-related protein {ECO:0000256|RuleBase:RU910716};
GN   Name=XKR7 {ECO:0000313|Ensembl:ENSLAFP00000020243.1};
OS   Loxodonta africana (African elephant).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX   NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000020243.1, ECO:0000313|Proteomes:UP000007646};
RN   [1] {ECO:0000313|Ensembl:ENSLAFP00000020243.1, ECO:0000313|Proteomes:UP000007646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000020243.1,
RC   ECO:0000313|Proteomes:UP000007646};
RA   Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Loxodonta africana (African elephant).";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLAFP00000020243.1}
RP   IDENTIFICATION.
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000020243.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU910716}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU910716}.
CC   -!- SIMILARITY: Belongs to the XK family. {ECO:0000256|ARBA:ARBA00008789,
CC       ECO:0000256|RuleBase:RU910716}.
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DR   AlphaFoldDB; G3TXD5; -.
DR   Ensembl; ENSLAFT00000032723.1; ENSLAFP00000020243.1; ENSLAFG00000030771.1.
DR   GeneTree; ENSGT01070000253766; -.
DR   HOGENOM; CLU_028534_1_0_1; -.
DR   Proteomes; UP000007646; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018629; XK-rel.
DR   PANTHER; PTHR16024; XK-RELATED PROTEIN; 1.
DR   PANTHER; PTHR16024:SF7; XK-RELATED PROTEIN 7; 1.
DR   Pfam; PF09815; XK-related; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910716};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW   Transmembrane {ECO:0000256|RuleBase:RU910716};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU910716}.
FT   TRANSMEM        58..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        89..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        176..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        303..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        326..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        358..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        384..402
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        414..437
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          466..498
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   577 AA;  63944 MW;  71F9A1E8C7948CF9 CRC64;
     MAAKSDGAAA AAGPEPEGVA GGPRGGAGGR GEAAAVAGGA GVTEAGGPGP RYELRDCCWV
     LCALLVFFSD GATDLWLAAS YYIQGQRTYF GLTLLFVLLP SLVVQLLSFR WFVYDYTDPA
     GPPGPAVSTK DSSVGGPVIS TKDSATAFRT KEGSPEVGSR PAPSSAHTYR RRCCRLCIWL
     LQTLVHLLQL GQVWRYLHAL YLGLQSRWRG ERLQRHFYWR MLFESADVSM LRLLETFLRS
     APQLVLQLSL IVHRSNSDSD SDIFSTFASL LSLAWTLASY QKVLRDSRDD KRPLSYKGAV
     VQVLWHLFTI AARSLAFALF ASVYKLYFGI FIVAHWCIMT FWVIQGETDF CMSKWEEIIY
     NMVVGIIYIF CWFNVKEGRS RRRMTLYYCI VLLENAALTG FWYSSRNSPL DRSLILVCVG
     ASSFALGIFF MCVYYCLLHP QWAHAGGPQA PGCICPEAPG PCGPPADAVT SPPRSLPRTE
     REGATVGGER PGTPTPPVFQ VRPGLPATPV ARTLRTEGPV IRIDLPRKKY PAWDAHFIDR
     RLRKTILALE YSSPATPRLQ YRSVGISQEL LEYETTV
//