ID G3TYD9_LOXAF Unreviewed; 643 AA.
AC G3TYD9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Cartilage acidic protein 1 {ECO:0000313|Ensembl:ENSLAFP00000020597.1};
GN Name=CRTAC1 {ECO:0000313|Ensembl:ENSLAFP00000020597.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000020597.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000020597.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000020597.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000020597.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000020597.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3TYD9; -.
DR Ensembl; ENSLAFT00000032096.1; ENSLAFP00000020597.1; ENSLAFG00000003369.3.
DR GeneTree; ENSGT00390000013726; -.
DR HOGENOM; CLU_027473_0_0_1; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR027039; Crtac1.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR011519; UnbV_ASPIC.
DR PANTHER; PTHR16026; CARTILAGE ACIDIC PROTEIN 1; 1.
DR PANTHER; PTHR16026:SF0; CARTILAGE ACIDIC PROTEIN 1; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF13517; FG-GAP_3; 2.
DR Pfam; PF07593; UnbV_ASPIC; 1.
DR SMART; SM00179; EGF_CA; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR PROSITE; PS01187; EGF_CA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..643
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003456032"
FT DOMAIN 551..598
FT /note="EGF-like calcium-binding"
FT /evidence="ECO:0000259|SMART:SM00179"
SQ SEQUENCE 643 AA; 69427 MW; 45B8C707C6C23D47 CRC64;
MLGMSLFLLL LGLLPPTEGS QRAEPMFTAV TNSVLPPDYD SNPTQLNYGV AVTDVDHDGD
FEIVVAGYNG PNLVLKYDRT LKRLVNIAVD ERSSPYYALR DRQGNAIGVT ACDIDGDGRE
EIYFLNTNNA FSGVATYSDK LFKFRNNRWE DILSDEVNVA RGVASLFAGR SVACVDRTGS
GRYSIYIANY AYGNVGPDAL IEMDPEASDL SRGILALRDV AAEAGVSKYT GGRGVSVGPI
LSSSASDIFC DNENGPNFLF HNRGDGTFVD AAASAGVDDP HQHGRGVALA DFNRDGKVDI
VYGNWNGPHR LYLQMNVHGK VRFRDIASPK FSMPSPVRTV IAADFDNDQE LEVFFNNIAY
RSSSANRLFR VIRREHGDPL IEELNPGDAL EPEGRGTGGV VTDFDGDGML DLILSHGESM
AQPLSVFRGN QGFSNNWLRV VPRTRFGAFA RGAKVVLYTK RSGAHLRIID GGSGYLCEME
PVAHFGLGKD EASSVEVTWP DGKMVSRSVA SGEMNSVLEI PYPRDEDKFQ DPAPLECGQG
FSQQENGHCM DTNECIQFPF VCPRDKPVCV NTYGSYRCRT NKRCSQGYEP NEDGTACVGT
FGQSPGRRST TPTTAAAAAA AAAAAGAATA APVLVDGDLD LGS
//
