ID G3U2J5_LOXAF Unreviewed; 689 AA.
AC G3U2J5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Zinc finger and BTB domain containing 48 {ECO:0000313|Ensembl:ENSLAFP00000022053.1};
GN Name=ZBTB48 {ECO:0000313|Ensembl:ENSLAFP00000022053.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000022053.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000022053.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000022053.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000022053.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000022053.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; G3U2J5; -.
DR STRING; 9785.ENSLAFP00000022053; -.
DR Ensembl; ENSLAFT00000030563.1; ENSLAFP00000022053.1; ENSLAFG00000005854.3.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000158981; -.
DR InParanoid; G3U2J5; -.
DR OMA; EPPGNRK; -.
DR TreeFam; TF331310; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:Ensembl.
DR GO; GO:0003691; F:double-stranded telomeric DNA binding; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0010833; P:telomere maintenance via telomere lengthening; IEA:Ensembl.
DR CDD; cd18232; BTB_POZ_ZBTB48_TZAP_KR3; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 9.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24394:SF29; GM08392P; 1.
DR PANTHER; PTHR24394; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF00096; zf-C2H2; 5.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 6.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 9.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 10.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 26..89
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 291..314
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 351..378
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 379..407
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 408..436
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 437..465
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 466..493
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 494..521
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 522..550
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 551..578
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 579..606
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 123..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..215
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 689 AA; 76962 MW; E547AAB39C247551 CRC64;
MDGSFVQHSV KVLQELNKQR ETGQYCDATL DVGGLVFKAH WSVLACSSHF FQSLYGDGSG
GSVVLPAGFS EIFGLLLDFF YTGHLALTSG NRDQVLLAAR ELRVPEAVEL CQSFKAQNLV
GQAPSGQSEL GKPASQDGSS CLKESADLEE EEVAGTLGQA PRGQDTSSSH SPQRPPLCPP
AQSESPSFLH GKFRQALRPG PPEDKEPEDC KVPPRPLEAE GVQLQGGSHE WEVVVQVEDD
GEGDYVSEPD TVSAKRKSNV IMKACAAEPA LGSGSPMAEP AENRRGAVGP VECPTCHKKF
LSKYYLKVHN REHASLLGHP LSLCSGQCYF RKENLLEHEA RNCMTRSEQV FTCSVCQETF
RRRMELRVHM VSHTGEMPYK CSSCSQQFMQ KKDLQSHMIK LHGAPKPHAC PTCAKCFLSR
TELQLHEAFK HRGEKLFVCE ECGHRASSRN GLQMHIKAKH RNERPYVCEF CSHAFTQKAN
LNMHLRTHTG EKPFQCHLCG KTFRTQASLD KHNRTHTGER PFSCEFCEQR FTEKGPLLRH
VASRHQEGRP HFCQICGKTF KAVEQLRVHV RRHKGVRKFE CTECGYKFTR QAHLRRHMEI
HDRVENYNPR QRKLRNLIIE DEKMVVVALQ PPAELEVSSA EVIVESLAQG SLASQLPSQR
LCADESFAGP GVMESSLIIT AAIPEDCDT
//
