ID G3U423_LOXAF Unreviewed; 190 AA.
AC G3U423;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=EBF transcription factor 1 {ECO:0000313|Ensembl:ENSLAFP00000022581.1};
GN Name=EBF1 {ECO:0000313|Ensembl:ENSLAFP00000022581.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000022581.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000022581.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000022581.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000022581.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000022581.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004489}.
CC -!- SIMILARITY: Belongs to the COE family. {ECO:0000256|RuleBase:RU004489}.
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DR AlphaFoldDB; G3U423; -.
DR Ensembl; ENSLAFT00000031934.1; ENSLAFP00000022581.1; ENSLAFG00000017522.4.
DR GeneTree; ENSGT00950000182859; -.
DR HOGENOM; CLU_016320_1_1_1; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.287.4280; -; 1.
DR InterPro; IPR032201; COE_HLH.
DR InterPro; IPR003523; Transcription_factor_COE.
DR PANTHER; PTHR10747; TRANSCRIPTION FACTOR COE FAMILY MEMBER; 1.
DR PANTHER; PTHR10747:SF26; TRANSCRIPTION FACTOR COE1; 1.
DR Pfam; PF16423; COE1_HLH; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|RuleBase:RU004489};
KW DNA-binding {ECO:0000256|RuleBase:RU004489};
KW Metal-binding {ECO:0000256|RuleBase:RU004489};
KW Nucleus {ECO:0000256|RuleBase:RU004489};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Transcription {ECO:0000256|RuleBase:RU004489};
KW Transcription regulation {ECO:0000256|RuleBase:RU004489};
KW Zinc {ECO:0000256|RuleBase:RU004489};
KW Zinc-finger {ECO:0000256|RuleBase:RU004489}.
FT DOMAIN 2..45
FT /note="Transcription factor COE helix-loop-helix"
FT /evidence="ECO:0000259|Pfam:PF16423"
FT REGION 112..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 190 AA; 20341 MW; DF043FC34157040E CRC64;
ALNEPTIDYG FQRLQKVIPR HPGDPERLPK EVILKRAADL VEALYGMPHN NQEIILKRAA
DIAEALYSVP RNHNQLPALA NTSVHAGMMG VNSFSGQLAV NVSEASQATN QGFTRNSSSV
SPHGYVPSTT PQQTNYNSVT TSMNGYGTAA MSNLGGSPTF LNGSAANSPY AKGLGILLWG
PLRRSPRPKS
//
