ID   G3U5P1_LOXAF            Unreviewed;       311 AA.
AC   G3U5P1;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
OS   Loxodonta africana (African elephant).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX   NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000023149.1, ECO:0000313|Proteomes:UP000007646};
RN   [1] {ECO:0000313|Ensembl:ENSLAFP00000023149.1, ECO:0000313|Proteomes:UP000007646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000023149.1,
RC   ECO:0000313|Proteomes:UP000007646};
RA   Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Loxodonta africana (African elephant).";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLAFP00000023149.1}
RP   IDENTIFICATION.
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000023149.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363047};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|RuleBase:RU000688}.
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DR   AlphaFoldDB; G3U5P1; -.
DR   STRING; 9785.ENSLAFP00000023149; -.
DR   Ensembl; ENSLAFT00000017518.3; ENSLAFP00000023149.1; ENSLAFG00000017519.3.
DR   eggNOG; ENOG502T9KT; Eukaryota.
DR   GeneTree; ENSGT00940000162330; -.
DR   HOGENOM; CLU_012526_1_0_1; -.
DR   InParanoid; G3U5P1; -.
DR   OMA; PFTCIII; -.
DR   TreeFam; TF337210; -.
DR   Proteomes; UP000007646; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   CDD; cd15918; 7tmA_OR1_7-like; 1.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   PANTHER; PTHR48001; OLFACTORY RECEPTOR; 1.
DR   PANTHER; PTHR48001:SF15; OLFACTORY RECEPTOR; 1.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|RuleBase:RU363047};
KW   G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363047};
KW   Olfaction {ECO:0000256|RuleBase:RU363047};
KW   Receptor {ECO:0000256|RuleBase:RU000688};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW   Sensory transduction {ECO:0000256|RuleBase:RU363047};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000688};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM        26..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        60..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        99..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        140..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        197..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        242..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        272..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   DOMAIN          41..289
FT                   /note="G-protein coupled receptors family 1 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50262"
SQ   SEQUENCE   311 AA;  35270 MW;  33EADD8F01DD6430 CRC64;
     MDRENQTRVT EFLLLGFSGE PEQEKILFGM FMWMYLVTIT GNFLITLAIT CDSHLHKPMY
     FFLANLSCVD ICFSSVTTPK MLVNHMLGNE SISYVECMIQ IYFFITFINM DGFLLSVMAY
     DRYVAICSPL HYSMIMRPKL CVLLVAVSWI ITNMHALLHT LLMVQLMFCS NNAVHHFFCD
     PYAILKLSCS DTFINELMIS TAGGLMSITP FTCITVSYAY IFSNVLKFPS IQAIRKALST
     CGSHLTVVSL FYGAILGVYM HPSSSYSVQD TVATVIFTVV TPLVNPFIYS LRNYDMKGSL
     RKLIIRRLVS P
//